Methods:

Nenad Sarapa, Justin L. Mortara, Barry D. Brown, Lamberto Isola, and Fabio Badilini

Quantitative Performance of E-Scribe Warehouse in Detecting Quality Issues With Digital Annotated ECG Data From Healthy Subjects
J Clin Pharmacol 2008 48: 538 -546. [Abstract] [Full Text] [PDF]  

Pharmacokinetics:

Ashok Jain, Raman Venkataramanan, Rajeev Sharma, Tai Kwong, Peter Abt, Mark Orloff, Randeep Kashyap, Georgious Tsoulfas, and Adel Bozorgzadeh

Pharmacokinetics of Mycophenolic Acid in Live Donor Liver Transplant Patients vs Deceased Donor Liver Transplant Patients
J Clin Pharmacol 2008 48: 547 -552. [Abstract] [Full Text] [PDF]  

Cheri E. Klein, Yi-Lin Chiu, Yan Cai, Katrin Beck, Kathryn R. King, Sonja J. Causemaker, Thao Doan, Hans-Ulrich Esslinger, Thomas J. Podsadecki, and George J. Hanna

Effects of Acid-Reducing Agents on the Pharmacokinetics of Lopinavir/Ritonavir and Ritonavir-Boosted Atazanavir
J Clin Pharmacol 2008 48: 553 -562. [Abstract] [Full Text] [PDF]  

Claire Souppart, Anne Gardin, Gerard Greig, Sebastien Balez, Yannick Batard, Axel Krebs-Brown, and Silke Appel-Dingemanse

Pharmacokinetics of Licarbazepine in Healthy Volunteers: Single and Multiple Oral Doses and Effect of Food
J Clin Pharmacol 2008 48: 563 -569. [Abstract] [Full Text] [PDF]  

Pharmacokinetics and Pharmacodynamics:

Karen May, Kristin Westphal, Thomas Giessmann, Danilo Wegner, Ulrike Adam, Markus M. Lerch, Reinhard Oertel, Rolf W. Warzok, Werner Weitschies, Manfred Braeter, and Werner Siegmund

Disposition and Antimuscarinic Effects of the Urinary Bladder Spasmolytics Propiverine: Influence of Dosage Forms and Circadian-Time Rhythms
J Clin Pharmacol 2008 48: 570 -579. [Abstract] [Full Text] [PDF]  

Hans J. Roethig, Shixia Feng, Qiwei Liang, Jianmin Liu, William A. Rees, and Barbara K. Zedler

A 12-Month, Randomized, Controlled Study to Evaluate Exposure and Cardiovascular Risk Factors in Adult Smokers Switching From Conventional Cigarettes to a Second-Generation Electrically Heated Cigarette Smoking System
J Clin Pharmacol 2008 48: 580 -591. [Abstract] [Full Text] [PDF]  

Goutam C. Mistry, Andrea L. Maes, Kenneth C. Lasseter, Michael J. Davies, Keith M. Gottesdiener, John A. Wagner, and Gary A. Herman

Effect of Sitagliptin, a Dipeptidyl Peptidase-4 Inhibitor, on Blood Pressure in Nondiabetic Patients With Mild to Moderate Hypertension
J Clin Pharmacol 2008 48: 592 -598. [Abstract] [Full Text] [PDF]  

Drug Interactions:

Lawrence S. Lee, Stephen D. Wise, Clark Chan, Teresa L. Parsons, Charles Flexner, and Paul S. Lietman

Possible Differential Induction of Phase 2 Enzyme and Antioxidant Pathways by American Ginseng, Panax quinquefolius
J Clin Pharmacol 2008 48: 599 -609. [Abstract] [Full Text] [PDF]  

Rebecca E. Wrishko, Jasper Dingemanse, Albert Yu, Christelle Darstein, Diane L. Phillips, and Malcolm I. Mitchell

Pharmacokinetic Interaction Between Tadalafil and Bosentan in Healthy Male Subjects
J Clin Pharmacol 2008 48: 610 -618. [Abstract] [Full Text] [PDF]  

Quantitative Clinical Pharmacology:

Camilla Staahl, Richard Upton, David J. R. Foster, Lona Louring Christrup, Kim Kristensen, Steen Honoré Hansen, Lars Arendt-Nielsen, and Asbjørn Mohr Drewes

Pharmacokinetic-Pharmacodynamic Modeling of Morphine and Oxycodone Concentrations and Analgesic Effect in a Multimodal Experimental Pain Model
J Clin Pharmacol 2008 48: 619 -631. [Abstract] [Full Text] [PDF]  

Forum:

Jeffrey S. Barrett, Michael J. Fossler, K. David Cadieu, and Marc R. Gastonguay

Pharmacometrics: A Multidisciplinary Field to Facilitate Critical Thinking in Drug Development and Translational Research Settings
J Clin Pharmacol 2008 48: 632 -649. [Abstract] [Full Text] [PDF]  

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