ACCP Position Statement:

Barbara Ameer and Norberto Krivoy

Direct-to-Consumer/Patient Advertising of Genetic Testing: A Position Statement of the American College of Clinical Pharmacology
J Clin Pharmacol 2009 49: 886 -888. [Full Text] [PDF] [Request Permission]

Special Populations:

Stephanie Läer, Jeffrey S. Barrett, and Bernd Meibohm

The In Silico Child: Using Simulation to Guide Pediatric Drug Development and Manage Pediatric Pharmacotherapy
J Clin Pharmacol 2009 49: 889 -904. [Abstract] [Full Text] [PDF] [Request Permission]

Methods:

Benoît Tyl, Meriam Kabbaj, Basmah Fassi, Patrick De Jode, and William Wheeler

Comparison of Semiautomated and Fully Automated Methods for QT Measurement During a Thorough QT/QTc Study: Variability and Sample Size Considerations
J Clin Pharmacol 2009 49: 905 -915. [Abstract] [Full Text] [PDF] [Request Permission]

Pharmacokinetics and Pharmacodynamics:

Hea-Young Cho, Robert A. Blum, Tracey Sunderland, Garth J. S. Cooper, and William J. Jusko

Pharmacokinetic and Pharmacodynamic Modeling of a Copper-Selective Chelator (TETA) in Healthy Adults
J Clin Pharmacol 2009 49: 916 -928. [Abstract] [Full Text] [PDF] [Request Permission]

Pharmacodynamics:

Yan-Mei Mao, Zhao-Qian Liu, Bi-Lian Chen, Dong Guo, Chun-Ting Han, Li-Jun Yang, Sai-Ying Wang, Lan Fan, and Hong-Hao Zhou

Effect of 393T>C Polymorphism of GNAS1 Gene on Dobutamine Response in Chinese Healthy Subjects
J Clin Pharmacol 2009 49: 929 -936. [Abstract] [Full Text] [PDF] [Request Permission]

Daniel M. Bloomfield, Rajesh Krishna, David Hreniuk, Lisa Hickey, Kalyan Ghosh, Arthur J. Bergman, Jutta Miller, Maria J. Gutierrez, Randall Stoltz, Keith M. Gottesdiener, Gary A. Herman, and John A. Wagner

A Thorough QTc Study to Assess the Effect of Sitagliptin, a DPP4 Inhibitor, on Ventricular Repolarization in Healthy Subjects
J Clin Pharmacol 2009 49: 937 -946. [Abstract] [Full Text] [PDF] [Supplementary Tables] [Request Permission]

Jian-Jun Li, Zong-Liang Lu, Wen-Rong Kou, Zuo Chen, Yang-Feng Wu, Xue-Hai Yu, Yu-Cheng Zhao on behalf of the Chinese Coronary Secondary Prevention Study Group

Beneficial Impact of Xuezhikang on Cardiovascular Events and Mortality in Elderly Hypertensive Patients With Previous Myocardial Infarction From the China Coronary Secondary Prevention Study (CCSPS)
J Clin Pharmacol 2009 49: 947 -956. [Abstract] [Full Text] [PDF] [Request Permission]

Filippia Aroni, Nicoletta Iacovidou, Ismene Dontas, Chryssa Pourzitaki, and Theodoros Xanthos

Pharmacological Aspects and Potential New Clinical Applications of Ketamine: Reevaluation of an Old Drug
J Clin Pharmacol 2009 49: 957 -964. [Abstract] [Full Text] [PDF] [Request Permission]

Pharmacokinetics:

Carolina de Miranda Silva, Bruno José Dumêt Fernandes, Eduardo Antônio Donadi, Lucienir Maria Silva, Eduardo Barbosa Coelho, Márcio Dantas, Maria Paula Marques, and Vera Lucia Lanchote

Influence of Glomerular Filtration Rate on the Pharmacokinetics of Cyclophosphamide Enantiomers in Patients With Lupus Nephritis
J Clin Pharmacol 2009 49: 965 -972. [Abstract] [Full Text] [PDF] [Request Permission]

C. Steven Ernest, II, Michael A. Heathman, and Rebecca E. Wrishko

Prediction of Prasugrel Active Metabolite Concentrations From 2 Downstream Inactive Metabolite Concentrations Using Multilinear Regression Analysis
J Clin Pharmacol 2009 49: 973 -983. [Abstract] [Full Text] [PDF] [Request Permission]

Rebecca E. Wrishko, C. Steven Ernest, II, David S. Small, Ying G. Li, Govinda J. Weerakkody, Jeffrey R. Riesmeyer, William L. Macias, Shashank Rohatagi, Daniel E. Salazar, Elliott M. Antman, Stephen D. Wiviott, Eugene Braunwald, and Lan Ni

Population Pharmacokinetic Analyses to Evaluate the Influence of Intrinsic and Extrinsic Factors on Exposure of Prasugrel Active Metabolite in TRITON-TIMI 38
J Clin Pharmacol 2009 49: 984 -998. [Abstract] [Full Text] [PDF] [Request Permission]

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.