Commentary:

Neville F. Ford

Clopidogrel Resistance: Pharmacokinetic or Pharmacogenetic?
J Clin Pharmacol 2009 49: 506 -512. [Abstract] [Full Text] [PDF] [Request Permission]

Review:

Natilie A. Hosea, Wendy T. Collard, Susan Cole, Tristan S. Maurer, Rick X. Fang, Hannah Jones, Shefali M. Kakar, Yasuhiro Nakai, Bill J. Smith, Rob Webster, and Kevin Beaumont

Prediction of Human Pharmacokinetics From Preclinical Information: Comparative Accuracy of Quantitative Prediction Approaches
J Clin Pharmacol 2009 49: 513 -533. [Abstract] [Full Text] [PDF] [Request Permission]

Methods:

Xiaoping Zhang, Mariabeth Silkey, Marta Schumacher, Lei Wang, Hiral Raval, and John P. Caulfield

Period Correction of the QTc of Moxifloxacin With Multiple Predose Baseline ECGs Is the Least Variable of 4 Methods Tested
J Clin Pharmacol 2009 49: 534 -539. [Abstract] [Full Text] [PDF] [Request Permission]

John Z. Duan

Two Commonly Used Methods for Exposure–Adverse Events Analysis: Comparisons and Evaluations
J Clin Pharmacol 2009 49: 540 -552. [Abstract] [Full Text] [PDF] [Request Permission]

Pharmacokinetics and Pharmacodynamics:

Carol M. MacLean, Anna-Tina Casanova, Luisa Baselgia-Jeker, Nicola Neave, Finn Larsen, Laurence Skillern, Juergen Drewe, and Christoph Beglinger

Effect of Food on the Pharmacokinetics and Pharmacodynamics of an Oral Ghrelin Agonist (ARD-07) in Healthy Subjects
J Clin Pharmacol 2009 49: 553 -559. [Abstract] [Full Text] [PDF] [Request Permission]

Drug Interactions:

Aernout D. van Haarst, Anneke C. Dijkmans, Hans-Josef Weimann, Michiel J. B. Kemme, Jacobus J. Bosch, Rik C. Schoemaker, Adam F. Cohen, and Jacobus Burggraaf

Clinically Important Interaction Between Tedisamil and Verapamil
J Clin Pharmacol 2009 49: 560 -567. [Abstract] [Full Text] [PDF] [Request Permission]

Makiko Kokudai, Naoki Inui, Kazuhiko Takeuchi, Toshiyuki Sakaeda, Yoshiyuki Kagawa, and Hiroshi Watanabe

Effects of Statins on the Pharmacokinetics of Midazolam in Healthy Volunteers
J Clin Pharmacol 2009 49: 568 -573. [Abstract] [Full Text] [PDF] [Request Permission]

B. L. Chen, Y. Chen, J. H. Tu, Y. L. Li, W. Zhang, Q. Li, L. Fan, Z. R. Tan, D. L. Hu, D. Wang, L. S. Wang, D. S. OuYang, and H. H. Zhou

Clopidogrel Inhibits CYP2C19-Dependent Hydroxylation of Omeprazole Related to CYP2C19 Genetic Polymorphisms
J Clin Pharmacol 2009 49: 574 -581. [Abstract] [Full Text] [PDF] [Request Permission]

Pharmacodynamics:

Concepción Pérez, María T. Saldaña, Ana Navarro, Silvia Martínez, and Javier Rejas

Trigeminal Neuralgia Treated With Pregabalin in Family Medicine Settings: Its Effect on Pain Alleviation and Cost Reduction
J Clin Pharmacol 2009 49: 582 -590. [Abstract] [Full Text] [PDF] [Request Permission]

Yongqing Wang, Yanli Zhou, Ling Meng, Xinzheng Lu, Ning Ou, and Xinli Li

Inflammatory Mediators in Chinese Patients With Congestive Heart Failure
J Clin Pharmacol 2009 49: 591 -599. [Abstract] [Full Text] [PDF] [Request Permission]

Brief Report/Pharmacodynamics:

Bridgette L. Jones, Susan M. Abdel-Rahman, Steve D. Simon, Gregory L. Kearns, and Kathleen A. Neville

Assessment of Histamine Pharmacodynamics by Microvasculature Response of Histamine Using Histamine Iontophoresis Laser Doppler Flowimetry
J Clin Pharmacol 2009 49: 600 -605. [Full Text] [PDF] [Request Permission]

Pharmacokinetics:

Alyson Connor, Phil Evans, Judy Doto, Corey Ellis, and David E. Martin

An Oral Human Drug Absorption Study to Assess the Impact of Site of Delivery on the Bioavailability of Bevirimat
J Clin Pharmacol 2009 49: 606 -612. [Abstract] [Full Text] [PDF] [Request Permission]

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