Innovation and Viewpoints:

Thaddeus H. Grasela, Elizabeth Ludwig, and Jill Fiedler-Kelly

Kerfuffle!
J Clin Pharmacol 2009 49: 386 -388. [Abstract] [Full Text] [PDF] [Request Permission]

Drug Interactions:

Gabriele M. Böhmer, Nassr Nassr, Marcus Wenger, Andreas Hünnemeyer, Gezim Lahu, Silke Templin, Christoph H. Gleiter, and Robert Hermann

The Targeted Oral, Once-Daily Phosphodiesterase 4 Inhibitor Roflumilast and the Leukotriene Receptor Antagonist Montelukast Do Not Exhibit Significant Pharmacokinetic Interactions
J Clin Pharmacol 2009 49: 389 -397. [Abstract] [Full Text] [PDF] [Request Permission]

S. A. Stoch, E. Friedman, A. Maes, K. Yee, Y. Xu, P. Larson, M. Fitzgerald, J. Chodakewitz, and J. A. Wagner

Effect of Different Durations of Ketoconazole Dosing on the Single-Dose Pharmacokinetics of Midazolam: Shortening the Paradigm
J Clin Pharmacol 2009 49: 398 -406. [Abstract] [Full Text] [PDF] [Request Permission]

Pharmacokinetics:

Daniel J. Cushing, Michael P. Adams, Warren D. Cooper, Peter R. Kowey, and Raymond J. Lipicky

Bioequivalence of 2 Intravenous Amiodarone Formulations in Healthy Participants
J Clin Pharmacol 2009 49: 407 -415. [Abstract] [Full Text] [PDF] [Request Permission]

Pharmacodynamics:

Victor Dishy, Fang Liu, David L. Ebel, George J. Atiee, Jane Royalty, Sandra Reilley, John F. Paolini, John A. Wagner, and Eseng Lai

Effects of Aspirin When Added to the Prostaglandin D₂ Receptor Antagonist Laropiprant on Niacin-Induced Flushing Symptoms
J Clin Pharmacol 2009 49: 416 -422. [Abstract] [Full Text] [PDF] [Request Permission]

Nervin Lawendy, Sriram Krishnaswami, Rong Wang, David Gruben, Courtney Cannon, Suzanne Swan, and Gary Chan

Effect of CP-690,550, an Orally Active Janus Kinase Inhibitor, on Renal Function in Healthy Adult Volunteers
J Clin Pharmacol 2009 49: 423 -429. [Abstract] [Full Text] [PDF] [Request Permission]

Pharmacokinetics and Pharmacodynamics:

Gilbert Lefèvre, Monika Büche, Greg Sedek, Steve Maton, Albert Enz, Ulrike Lorch, Cyriaque Sagan, and Silke Appel-Dingemanse

Similar Rivastigmine Pharmacokinetics and Pharmacodynamics in Japanese and White Healthy Participants Following the Application of Novel Rivastigmine Patch
J Clin Pharmacol 2009 49: 430 -443. [Abstract] [Full Text] [PDF] [Request Permission]

Weijiang Zhang, Jingtao Wu, and Stuart N. Atkinson

Effects of Dexlansoprazole MR, a Novel Dual Delayed Release Formulation of a Proton Pump Inhibitor, on Plasma Gastrin Levels in Healthy Subjects
J Clin Pharmacol 2009 49: 444 -454. [Abstract] [Full Text] [PDF] [Request Permission]

Pharmacokinetics/Special Populations:

Jasper Dingemanse, Atef Halabi, and Paul L. M. van Giersbergen

Influence of Liver Cirrhosis on the Pharmacokinetics, Pharmacodynamics, and Safety of Tezosentan
J Clin Pharmacol 2009 49: 455 -464. [Abstract] [Full Text] [PDF] [Request Permission]

Special Populations:

Thomas Marbury, James A. Dowell, Elyse Seltzer, and Mary Buckwalter

Pharmacokinetics of Dalbavancin in Patients With Renal or Hepatic Impairment
J Clin Pharmacol 2009 49: 465 -476. [Abstract] [Full Text] [PDF] [Request Permission]

Bimal Malhotra, Kuan Gandelman, Richard Sachse, and Nolan Wood

Assessment of the Effects of Renal Impairment on the Pharmacokinetic Profile of Fesoterodine
J Clin Pharmacol 2009 49: 477 -482. [Abstract] [Full Text] [PDF] [Request Permission]

Brief Report/Drug Interactions:

Arthur J. Bergman, Josee Cote, Andrea Maes, Jamie J. Zhao, Brad A. Roadcap, Li Sun, Robert J. Valesky, Amy Yang, Bart Keymeulen, Zissi Mathijs, Marina De Smet, Tine Laethem, Michael J. Davies, John A. Wagner, and Gary A. Herman

Effect of Sitagliptin on the Pharmacokinetics of Simvastatin
J Clin Pharmacol 2009 49: 483 -488. [Full Text] [PDF] [Request Permission]

Brief Report/Pharmacokinetics and Pharmacodynamics:

Giulia Ghibellini, Joohyun Park, Claire F. Brittain, Laura Iavarone, Anne C. Andorn, Norman Levy, and Keith T. Muir

Bupropion Has No Effect on Intraocular Pressure or Other Ophthalmologic Parameters After Single or Repeat Doses in Healthy Volunteers
J Clin Pharmacol 2009 49: 489 -495. [Full Text] [PDF] [Request Permission]

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