Special Populations:

Peiming Ma, Bing-Bing Yang, Yow-Ming Wang, Mark Peterson, Adimoolam Narayanan, Liviawati Sutjandra, Rachelle Rodriguez, and Andrew Chow

Population Pharmacokinetic Analysis of Panitumumab in Patients With Advanced Solid Tumors
J Clin Pharmacol 2009 49: 1142 -1156. [Abstract] [Full Text] [PDF] [Request Permission]

Pharmacokinetics and Pharmacodynamics:

D. Hamish Wright, Gary A. Herman, Andrea Maes, Qi Liu, Amy O. Johnson-Levonas, and John A. Wagner

Multiple Doses of Sitagliptin, a Selective DPP-4 Inhibitor, Do Not Meaningfully Alter Pharmacokinetics and Pharmacodynamics of Warfarin
J Clin Pharmacol 2009 49: 1157 -1167. [Abstract] [Full Text] [PDF] [Request Permission]

Patricia N. Sidharta, Paul L. M. van Giersbergen, and Jasper Dingemanse

Pharmacokinetics and Pharmacodynamics of the Urotensin-II Receptor Antagonist Palosuran in Healthy Male Subjects
J Clin Pharmacol 2009 49: 1168 -1175. [Abstract] [Full Text] [PDF] [Appendices] [Request Permission]

Pharmacodynamics:

Prasad S. Nishtala, Romano A. Fois, Andrew J. McLachlan, J. Simon Bell, Patrick J. Kelly, and Timothy F. Chen

Anticholinergic Activity of Commonly Prescribed Medications and Neuropsychiatric Adverse Events in Older People
J Clin Pharmacol 2009 49: 1176 -1184. [Abstract] [Full Text] [PDF] [Request Permission]

Drug Interactions:

Joseph R. Walker, Karen Brown, Shashank Rohatagi, Mohinder S. Bathala, Chao Xu, Prachi K. Wickremasingha, Daniel E. Salazar, and Donald E. Mager

Quantitative Structure-Property Relationships Modeling to Predict In Vitro and In Vivo Binding of Drugs to the Bile Sequestrant, Colesevelam (Welchol)
J Clin Pharmacol 2009 49: 1185 -1195. [Abstract] [Full Text] [PDF] [Request Permission]

Korbinian Rupprecht, Christoph Schmidt, Anne Raspé, Frank Schweda, Maria Shipkova, Wolfgang Fischer, Michael Bucher, Frieder Kees, and Lothar Faerber

Bioavailability of Mycophenolate Mofetil and Enteric-Coated Mycophenolate Sodium Is Differentially Affected by Pantoprazole in Healthy Volunteers
J Clin Pharmacol 2009 49: 1196 -1201. [Abstract] [Full Text] [PDF] [Request Permission]

Jules I. Schwartz, Nancy G. B. Agrawal, P. H. Wong, Jutta Miller, Kenneth Bachmann, Thomas Marbury, David Hoelscher, Paul F. Cavanaugh, Jr, and Keith Gottesdiener

Examination of the Effect of Increasing Doses of Etoricoxib on Oral Methotrexate Pharmacokinetics in Patients With Rheumatoid Arthritis
J Clin Pharmacol 2009 49: 1202 -1209. [Abstract] [Full Text] [PDF] [Request Permission]

Aziz Karim, Aziz Laurent, Melvin Munsaka, Elisabeth Wann, Penny Fleck, and Qais Mekki

Coadministration of Pioglitazone or Glyburide and Alogliptin: Pharmacokinetic Drug Interaction Assessment in Healthy Participants
J Clin Pharmacol 2009 49: 1210 -1219. [Abstract] [Full Text] [PDF] [Request Permission]

Matthijs van Luin, Angela Colbers, Corrien P. W. G. M. Verwey-van Wissen, Eleonora W. J. van Ewijk-Beneken-Kolmer, Mike van der Kolk, Arjen Hoitsma, Hugo Gomes da Silva, and David M. Burger

The Effect of Raltegravir on the Glucuronidation of Lamotrigine
J Clin Pharmacol 2009 49: 1220 -1227. [Abstract] [Full Text] [PDF] [Request Permission]

Carol Addy, Patricia Jumes, Kimberly Rosko, Susie Li, Hankun Li, Andrea Maes, Amy O. Johnson-Levonas, Jeffrey Chodakewitz, S. Aubrey Stoch, and John A. Wagner

Pharmacokinetics, Safety, and Tolerability of Phentermine in Healthy Participants Receiving Taranabant, a Novel Cannabinoid-1 Receptor (CB1R) Inverse Agonist
J Clin Pharmacol 2009 49: 1228 -1238. [Abstract] [Full Text] [PDF] [Request Permission]

Pharmacokinetics:

Josep M. Jansat, Rosa Lamarca, Gonzalo de Miquel, Andreas Schrödter, Barbara Miletzki, and Matthias Gurniak

Safety and Pharmacokinetics of Multiple Doses of Aclidinium Bromide, a Novel Long-Acting Muscarinic Antagonist for the Treatment of Chronic Obstructive Pulmonary Disease, in Healthy Participants
J Clin Pharmacol 2009 49: 1239 -1246. [Abstract] [Full Text] [PDF] [Request Permission]

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