Editorials:

Rajesh Krishna

Quantitative Clinical Pharmacology: Guidance for Authors and a Call for Papers
J Clin Pharmacol 2008 48: 898 -899. [Full Text] [PDF] [Request Permission]

Forum/Regulatory Science:

Henry J. Malinowski, Agnes Westelinck, Junko Sato, and Ting Ong

Same Drug, Different Dosing: Differences in Dosing for Drugs Approved in the United States, Europe, and Japan
J Clin Pharmacol 2008 48: 900 -908. [Abstract] [Full Text] [PDF] [Request Permission]

Pharmacokinetics:

Matthew D. Linnik, Anne M. O'Rourke, and Mark A. Crowther

Pharmacokinetics of High-Dose Abetimus Sodium in Normal Subjects With Specific Assessment of Effect on Coagulation
J Clin Pharmacol 2008 48: 909 -918. [Abstract] [Full Text] [PDF] [Request Permission]

Romain Séchaud, Anna Robeva, Rossella Belleli, and Sebastien Balez

Absolute Oral Bioavailability and Disposition of Deferasirox in Healthy Human Subjects
J Clin Pharmacol 2008 48: 919 -925. [Abstract] [Full Text] [PDF] [Request Permission]

Pharmacokinetics and Pharmacodynamics:

Reiner Frey, Wolfgang Mück, Sigrun Unger, Ulrike Artmeier-Brandt, Gerrit Weimann, and Georg Wensing

Single-Dose Pharmacokinetics, Pharmacodynamics, Tolerability, and Safety of the Soluble Guanylate Cyclase Stimulator BAY 63-2521: An Ascending-Dose Study in Healthy Male Volunteers
J Clin Pharmacol 2008 48: 926 -934. [Abstract] [Full Text] [PDF] [Request Permission]

Quantitative Clinical Pharmacology:

Craig R. Rayner, Pascal Chanu, Ronald Gieschke, Lauren M. Boak, and E. Niclas Jonsson

Population Pharmacokinetics of Oseltamivir When Coadministered With Probenecid
J Clin Pharmacol 2008 48: 935 -947. [Abstract] [Full Text] [PDF] [Request Permission]

Drug Interactions:

Ping Ji, Bharat Damle, Jingdong Xie, Steve E. Unger, Dennis M. Grasela, and Sanjeev Kaul

Pharmacokinetic Interaction Between Efavirenz and Carbamazepine After Multiple-Dose Administration in Healthy Subjects
J Clin Pharmacol 2008 48: 948 -956. [Abstract] [Full Text] [PDF] [Request Permission]

Drug Metabolism and Transport:

Shanshan Liu, Paul M. Beringer, Levita Hidayat, Adupa P. Rao, Stan Louie, Gilbert J. Burckart, and Bertrand Shapiro

Probenecid, but Not Cystic Fibrosis, Alters the Total and Renal Clearance of Fexofenadine
J Clin Pharmacol 2008 48: 957 -965. [Abstract] [Full Text] [PDF] [Request Permission]

Pediatrics:

Luis Almeida, Ioana Minciu, Teresa Nunes, Nicolina Butoianu, Amilcar Falcão, Sandra-Adriana Magureanu, and Patrício Soares-da-Silva

Pharmacokinetics, Efficacy, and Tolerability of Eslicarbazepine Acetate in Children and Adolescents With Epilepsy
J Clin Pharmacol 2008 48: 966 -977. [Abstract] [Full Text] [PDF] [Request Permission]

Kathleen A. Neville, Stanley J. Szefler, Susan M. Abdel-Rahman, Gezim Lahu, Karl Zech, Rolf Herzog, Thomas D. Bethke, Melanie C. Gleason, and Gregory L. Kearns

Single-Dose Pharmacokinetics of Roflumilast in Children and Adolescents
J Clin Pharmacol 2008 48: 978 -985. [Abstract] [Full Text] [PDF] [Request Permission]

Pharmacogenomics:

Johanna Hilli, Tuomas Korhonen, Miia Turpeinen, Juho Hokkanen, Sampo Mattila, and Kari Laine

The Effect of Oral Contraceptives on the Pharmacokinetics of Melatonin in Healthy Subjects With CYP1A2 g.-163C>A Polymorphism
J Clin Pharmacol 2008 48: 986 -994. [Abstract] [Full Text] [PDF] [Request Permission]

Brief Report/Pharmacokinetics:

Daniel S. Sitar, Fred Y. Aoki, and Eric J. Bow

Acyclovir Bioavailability in Patients With Acute Myelogenous Leukemia Treated With Daunorubicin and Cytarabine
J Clin Pharmacol 2008 48: 995 -998. [Full Text] [PDF] [Request Permission]

Letter to the Editor:

David F. Lehmann and Braj B. Lohray

A Lesson in Moderation: Applying Pharmacodynamics to Clarify the Relationship Between Thiazolidinediones and Adverse Vascular Outcomes in Type 2 Diabetes
J Clin Pharmacol 2008 48: 999 -1002. [Full Text] [PDF] [Request Permission]

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