Editorials:

Lisa L. von Moltke

From the Editor
J Clin Pharmacol 2008 48: 266. [Full Text] [PDF]  

Quantitative Clinical Pharmacology:

Nathanael L. Dirks, Arno Nolting, Andreas Kovar, and Bernd Meibohm

Population Pharmacokinetics of Cetuximab in Patients With Squamous Cell Carcinoma of the Head and Neck
J Clin Pharmacol 2008 48: 267. [Abstract] [Full Text] [PDF]  

Pharmacokinetics/Special Populations:

Marc Phillips, William Smith, Guhan Balan, and Suzanne Ward

Pharmacokinetics of Glucarpidase in Subjects With Normal and Impaired Renal Function
J Clin Pharmacol 2008 48: 279. [Abstract] [Full Text] [PDF]  

James J. Zimmerman, Alain Patat, Virginia Parks, Romain Moirand, and Kyle Matschke

Pharmacokinetics of Sirolimus (Rapamycin) in Subjects With Severe Hepatic Impairment
J Clin Pharmacol 2008 48: 285. [Abstract] [Full Text] [PDF]  

Pharmacokinetics:

Suma Krishnan and Yuxin Zhang

Relative Bioavailability of Lisdexamfetamine 70-mg Capsules in Fasted and Fed Healthy Adult Volunteers and in Solution: A Single-Dose, Crossover Pharmacokinetic Study
J Clin Pharmacol 2008 48: 293. [Abstract] [Full Text] [PDF]  

Pharmacodynamics:

John M. Kovarik, Gilles-Jacques Riviere, Daniel Neddermann, Steve Maton, Thomas L. Hunt, and Robert L. Schmouder

A Mechanistic Study to Assess Whether Isoproterenol Can Reverse the Negative Chronotropic Effect of Fingolimod
J Clin Pharmacol 2008 48: 303. [Abstract] [Full Text] [PDF]  

Pharmacogenomics:

Annikka Kalliokoski, Mikko Neuvonen, Pertti J. Neuvonen, and Mikko Niemi

Different Effects of SLCO1B1 Polymorphism on the Pharmacokinetics and Pharmacodynamics of Repaglinide and Nateglinide
J Clin Pharmacol 2008 48: 311. [Abstract] [Full Text] [PDF]  

Drug Interactions:

Monika Schöller-Gyüre, Wim van den Brink, Thomas N. Kakuda, Brian Woodfall, Goedele De Smedt, Hilde Vanaken, Tanja Stevens, Monika Peeters, Kati Vandermeulen, and Richard M. W. Hoetelmans

Pharmacokinetic and Pharmacodynamic Study of the Concomitant Administration of Methadone and TMC125 in HIV-Negative Volunteers
J Clin Pharmacol 2008 48: 322. [Abstract] [Full Text] [PDF]  

Tomoya Ohno, Kazuki Nakayama, Susumu Nakade, Junsaku Kitagawa, Shinya Ueda, Hiroyuki Miyabe, Yasuyuki Miyata, and Akihiro Ohnishi

Effect of Itraconazole on the Pharmacokinetics of Imidafenacin in Healthy Subjects
J Clin Pharmacol 2008 48: 330. [Abstract] [Full Text] [PDF]  

Clinical Studies:

Francis M. Gengo, Michelle Rainka, Matthew Robson, Michael F. Gengo, Alan Forrest, Maurice Hourihane, and Vernice Bates

Prevalence of Platelet Nonresponsiveness to Aspirin in Patients Treated for Secondary Stroke Prophylaxis and in Patients With Recurrent Ischemic Events
J Clin Pharmacol 2008 48: 335. [Abstract] [Full Text] [PDF]  

Therapeutic Review:

Richard N. Re and Julia L. Cook

The Basis of an Intracrine Pharmacology
J Clin Pharmacol 2008 48: 344. [Abstract] [Full Text] [PDF]  

Review/Methods:

Stephan Schmidt, Rebecca Banks, Vipul Kumar, Kenneth H. Rand, and Hartmut Derendorf

Clinical Microdialysis in Skin and Soft Tissues: An Update
J Clin Pharmacol 2008 48: 351. [Abstract] [Full Text] [PDF]  

Review/Drug Metabolism Transport:

Richard Callaghan, Emily Crowley, Simon Potter, and Ian D. Kerr

P-glycoprotein: So Many Ways to Turn It On
J Clin Pharmacol 2008 48: 365. [Abstract] [Full Text] [PDF]  

Brief Report/Pharmacoepidemiology:

Christopher Kenney, Christine Hunter, Anthony Davidson, and Joseph Jankovic

Metoclopramide, an Increasingly Recognized Cause of Tardive Dyskinesia
J Clin Pharmacol 2008 48: 379. [Full Text] [PDF]  

Highlights and Book Reviews:

N.A. Kshirsagar

Highlights and Book Reviews
J Clin Pharmacol 2008 48: 385. [Full Text] [PDF]  

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