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Contents: December 2008, Volume 48, Issue 12   [Index by Author] 
       Pharmacokinetics
       Pharmacokinetics and Pharmacodynamics
       Pharmacokinetics and Pharmacodynamics/Special Populations
       Quantitative Clinical Pharmacology
       Drug Metabolism
       Drug Interactions
       Pediatrics

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To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

Pharmacokinetics:

Kenneth C. Cundy, Srikonda Sastry, Wendy Luo, Joan Zou, Tristen L. Moors, and Daniel M. Canafax
Clinical Pharmacokinetics of XP13512, a Novel Transported Prodrug of Gabapentin
J Clin Pharmacol 2008 48: 1378 -1388. [Abstract] [Full Text] [PDF] [Request Permission]

Pharmacokinetics and Pharmacodynamics:

Prajakti A. Kothare, Helle Linnebjerg, Yoshitaka Isaka, Kazunori Uenaka, Ayuko Yamamura, Kwee Poo Yeo, Amparo de la Peña, Choo Hua Teng, Kenneth Mace, Mark Fineman, Hirofumi Shigeta, Yukikuni Sakata, and Shin Irie
Pharmacokinetics, Pharmacodynamics, Tolerability, and Safety of Exenatide in Japanese Patients With Type 2 Diabetes Mellitus
J Clin Pharmacol 2008 48: 1389 -1399. [Abstract] [Full Text] [PDF] [Request Permission]

Reiner Frey, Wolfgang Mück, Sigrun Unger, Ulrike Artmeier-Brandt, Gerrit Weimann, and Georg Wensing
Pharmacokinetics, Pharmacodynamics, Tolerability, and Safety of the Soluble Guanylate Cyclase Activator Cinaciguat (BAY 58-2667) in Healthy Male Volunteers
J Clin Pharmacol 2008 48: 1400 -1410. [Abstract] [Full Text] [PDF] [Request Permission]

Pharmacokinetics and Pharmacodynamics/Special Populations:

Joachim Stangier, Hildegard Stähle, Karin Rathgen, Willy Roth, and Kasra Shakeri-Nejad
Pharmacokinetics and Pharmacodynamics of Dabigatran Etexilate, an Oral Direct Thrombin Inhibitor, Are Not Affected by Moderate Hepatic Impairment
J Clin Pharmacol 2008 48: 1411 -1419. [Abstract] [Full Text] [PDF] [Request Permission]

Quantitative Clinical Pharmacology:

Shashank Rohatagi, Timothy J. Carrothers, JinYan Jin, William J. Jusko, Tatiana Khariton, Joseph Walker, Kenneth Truitt, and Daniel E. Salazar
Model-Based Development of a PPAR{gamma} Agonist, Rivoglitazone, to Aid Dose Selection and Optimize Clinical Trial Designs
J Clin Pharmacol 2008 48: 1420 -1429. [Abstract] [Full Text] [PDF] [Supplemental Figures and Appendix] [Request Permission]

Drug Metabolism:

Keon W. Kang and Yoon G. Kim
Bioequivalence Studies of Tibolone in Premenopausal Women and Effects on Expression of the Tibolone-Metabolizing Enzyme AKR1C (Aldo-Keto Reductase) Family Caused by Estradiol
J Clin Pharmacol 2008 48: 1430 -1437. [Abstract] [Full Text] [PDF] [Request Permission]

Drug Interactions:

N. B. Modi, S. Kell, J. Aquilina, and D. Rivas
Effect of Dapoxetine on the Pharmacokinetics and Hemodynamic Effects of Tamsulosin in Men on a Stable Dose of Tamsulosin
J Clin Pharmacol 2008 48: 1438 -1450. [Abstract] [Full Text] [PDF] [Request Permission]

Rebecca Spence, Arun Mandagere, Christopher Dufton, and Jürgen Venitz
Pharmacokinetics and Safety of Ambrisentan in Combination With Sildenafil in Healthy Volunteers
J Clin Pharmacol 2008 48: 1451 -1459. [Abstract] [Full Text] [PDF] [Request Permission]

Pediatrics:

Nicolas Gregoire, Luc Desfrere, Jean-Christophe Roze, Yves Kibleur, and Petra Koehne
Population Pharmacokinetic Analysis of Ibuprofen Enantiomers in Preterm Newborn Infants
J Clin Pharmacol 2008 48: 1460 -1468. [Abstract] [Full Text] [PDF] [Request Permission]

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


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