Pharmacokinetics:

Kenneth C. Cundy, Srikonda Sastry, Wendy Luo, Joan Zou, Tristen L. Moors, and Daniel M. Canafax

Clinical Pharmacokinetics of XP13512, a Novel Transported Prodrug of Gabapentin
J Clin Pharmacol 2008 48: 1378 -1388. [Abstract] [Full Text] [PDF] [Request Permission]

Pharmacokinetics and Pharmacodynamics:

Prajakti A. Kothare, Helle Linnebjerg, Yoshitaka Isaka, Kazunori Uenaka, Ayuko Yamamura, Kwee Poo Yeo, Amparo de la Peña, Choo Hua Teng, Kenneth Mace, Mark Fineman, Hirofumi Shigeta, Yukikuni Sakata, and Shin Irie

Pharmacokinetics, Pharmacodynamics, Tolerability, and Safety of Exenatide in Japanese Patients With Type 2 Diabetes Mellitus
J Clin Pharmacol 2008 48: 1389 -1399. [Abstract] [Full Text] [PDF] [Request Permission]

Reiner Frey, Wolfgang Mück, Sigrun Unger, Ulrike Artmeier-Brandt, Gerrit Weimann, and Georg Wensing

Pharmacokinetics, Pharmacodynamics, Tolerability, and Safety of the Soluble Guanylate Cyclase Activator Cinaciguat (BAY 58-2667) in Healthy Male Volunteers
J Clin Pharmacol 2008 48: 1400 -1410. [Abstract] [Full Text] [PDF] [Request Permission]

Pharmacokinetics and Pharmacodynamics/Special Populations:

Joachim Stangier, Hildegard Stähle, Karin Rathgen, Willy Roth, and Kasra Shakeri-Nejad

Pharmacokinetics and Pharmacodynamics of Dabigatran Etexilate, an Oral Direct Thrombin Inhibitor, Are Not Affected by Moderate Hepatic Impairment
J Clin Pharmacol 2008 48: 1411 -1419. [Abstract] [Full Text] [PDF] [Request Permission]

Quantitative Clinical Pharmacology:

Shashank Rohatagi, Timothy J. Carrothers, JinYan Jin, William J. Jusko, Tatiana Khariton, Joseph Walker, Kenneth Truitt, and Daniel E. Salazar

Model-Based Development of a PPAR Agonist, Rivoglitazone, to Aid Dose Selection and Optimize Clinical Trial Designs
J Clin Pharmacol 2008 48: 1420 -1429. [Abstract] [Full Text] [PDF] [Supplemental Figures and Appendix] [Request Permission]

Drug Metabolism:

Keon W. Kang and Yoon G. Kim

Bioequivalence Studies of Tibolone in Premenopausal Women and Effects on Expression of the Tibolone-Metabolizing Enzyme AKR1C (Aldo-Keto Reductase) Family Caused by Estradiol
J Clin Pharmacol 2008 48: 1430 -1437. [Abstract] [Full Text] [PDF] [Request Permission]

Drug Interactions:

N. B. Modi, S. Kell, J. Aquilina, and D. Rivas

Effect of Dapoxetine on the Pharmacokinetics and Hemodynamic Effects of Tamsulosin in Men on a Stable Dose of Tamsulosin
J Clin Pharmacol 2008 48: 1438 -1450. [Abstract] [Full Text] [PDF] [Request Permission]

Rebecca Spence, Arun Mandagere, Christopher Dufton, and Jürgen Venitz

Pharmacokinetics and Safety of Ambrisentan in Combination With Sildenafil in Healthy Volunteers
J Clin Pharmacol 2008 48: 1451 -1459. [Abstract] [Full Text] [PDF] [Request Permission]

Pediatrics:

Nicolas Gregoire, Luc Desfrere, Jean-Christophe Roze, Yves Kibleur, and Petra Koehne

Population Pharmacokinetic Analysis of Ibuprofen Enantiomers in Preterm Newborn Infants
J Clin Pharmacol 2008 48: 1460 -1468. [Abstract] [Full Text] [PDF] [Request Permission]

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