Quantitative Clinical Pharmacology:

Guowei Dai, Marc Pfister, Anne Blackwood-Chirchir, and Amit Roy

Importance of Characterizing Determinants of Variability in Exposure: Application to Dasatinib in Subjects With Chronic Myeloid Leukemia
J Clin Pharmacol 2008 48: 1254 -1269. [Abstract] [Full Text] [PDF] [Appendix A] [Request Permission]

Anders Viberg, Otto Cars, Mats O. Karlsson, and Siv Jönsson

Estimation of Cefuroxime Dosage Using Pharmacodynamic Targets, MIC Distributions, and Minimization of a Risk Function
J Clin Pharmacol 2008 48: 1270 -1281. [Abstract] [Full Text] [PDF] [Request Permission]

Marie-Claude Gagnieu, Mirna El Barkil, Jean-Michel Livrozet, Laurent Cotte, Patrick Miailhes, André Boibieux, Jérôme Guitton, and Michel Tod

Population Pharmacokinetics of Tenofovir in AIDS Patients
J Clin Pharmacol 2008 48: 1282 -1288. [Abstract] [Full Text] [PDF] [Request Permission]

Pharmacokinetics:

Jean-Francois Marier, Martin Beliveau, Mohamad-Samer Mouksassi, Paula Shaw, Jane Cyran, Jothi Kesavan, John Wallens, Hamim Zahir, David Wells, and John Caminis

Pharmacokinetics, Safety, and Tolerability of Teduglutide, a Glucagon-Like Peptide-2 (GLP-2) Analog, Following Multiple Ascending Subcutaneous Administrations in Healthy Subjects
J Clin Pharmacol 2008 48: 1289 -1299. [Abstract] [Full Text] [PDF] [Request Permission]

Ann Tronde, Michael Gillen, Lars Borgström, Jan Lötvall, and Jaro Ankerst

Pharmacokinetics of Budesonide and Formoterol Administered Via 1 Pressurized Metered-Dose Inhaler in Patients With Asthma and COPD
J Clin Pharmacol 2008 48: 1300 -1308. [Abstract] [Full Text] [PDF] [Request Permission]

Shashank Rohatagi, James Lee, Magdy Shenouda, Stephen Haworth, Mohinder Singh Bathala, Mark Allison, Igor Rubets, Reinilde Heyrman, Robert Noveck, and Daniel E. Salazar

Pharmacokinetics of Amlodipine and Olmesartan After Administration of Amlodipine Besylate and Olmesartan Medoxomil in Separate Dosage Forms and as a Fixed-Dose Combination
J Clin Pharmacol 2008 48: 1309 -1322. [Abstract] [Full Text] [PDF] [Request Permission]

Drug Interactions/Disposition:

Sujata Vaidyanathan, Gian Camenisch, Helmut Schuetz, Christine Reynolds, Ching-Ming Yeh, Marie-Noelle Bizot, Hans Armin Dieterich, Dan Howard, and William P. Dole

Pharmacokinetics of the Oral Direct Renin Inhibitor Aliskiren in Combination With Digoxin, Atorvastatin, and Ketoconazole in Healthy Subjects: The Role of P-Glycoprotein in the Disposition of Aliskiren
J Clin Pharmacol 2008 48: 1323 -1338. [Abstract] [Full Text] [PDF] [Request Permission]

Drug Interactions:

Gezim Lahu, Andreas Huennemeyer, Oliver von Richter, Robert Hermann, Rolf Herzog, Nigel McCracken, and Karl Zech

Effect of Single and Repeated Doses of Ketoconazole on the Pharmacokinetics of Roflumilast and Roflumilast N-Oxide
J Clin Pharmacol 2008 48: 1339 -1349. [Abstract] [Full Text] [PDF] [Request Permission]

Review/Drug Metabolism:

David J. Greenblatt and Lisa L. von Moltke

Gender Has a Small but Statistically Significant Effect on Clearance of CYP3A Substrate Drugs
J Clin Pharmacol 2008 48: 1350 -1355. [Abstract] [Full Text] [PDF] [Request Permission]

Pediatrics:

Gregory L. Kearns, Jeffrey Blumer, Stephen Schexnayder, Laura P. James, Kim G. Adcock, Michael D. Reed, James F. Daniel, Andrea Gaedigk, and Jeffrey Paul

Single-Dose Pharmacokinetics of Oral and Intravenous Pantoprazole in Children and Adolescents
J Clin Pharmacol 2008 48: 1356 -1365. [Abstract] [Full Text] [PDF] [Request Permission]

Errata:

J Clin Pharmacol 2008 48: 1366 -1367. [Full Text] [PDF] [Request Permission]

J Clin Pharmacol 2008 48: 1368 . [Full Text] [PDF] [Request Permission]

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.