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Contents: September 2007, Volume 47, Issue 9   [Index by Author] 
       Clinical Trials
       Pharmacogenomics
       Biologics
       Clinical Studies
       Pharmacokinetics and Pharmacodynamics
       Pharmacokinetics
       Quantitative Clinical Pharmacology
       Pediatrics
       Letter to the Editor
       ACCP Announcements
 
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To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

Clinical Trials:

Stephen P. Glasser, Maribel Salas, and Elizabeth Delzell
Importance and Challenges of Studying Marketed Drugs: What Is a Phase IV Study? Common Clinical Research Designs, Registries, and Self-Reporting Systems
J Clin Pharmacol 2007 47: 1074. [Abstract] [Full Text] [PDF]  

Pharmacogenomics:

Michael H. Court
A Pharmacogenomics Primer
J Clin Pharmacol 2007 47: 1087. [Abstract] [Full Text] [PDF]  

Biologics:

Kathleen Seitz and Honghui Zhou
Pharmacokinetic Drug-Drug Interaction Potentials for Therapeutic Monoclonal Antibodies: Reality Check
J Clin Pharmacol 2007 47: 1104. [Abstract] [Full Text] [PDF]  

Ferdinand Breedveld, Sunil Agarwal, Ming Yin, Song Ren, Nicole F. Li, Tim M. Shaw, and Brian E. Davies
Rituximab Pharmacokinetics in Patients With Rheumatoid Arthritis: B-Cell Levels Do Not Correlate With Clinical Response
J Clin Pharmacol 2007 47: 1119. [Abstract] [Full Text] [PDF]  

Clinical Studies:

Fabrice Extramiana, Fabio Badilini, Nenad Sarapa, Antoine Leenhardt, and Pierre Maison-Blanche
Contrasting Time- and Rate-Based Approaches for the Assessment of Drug-Induced QT Changes
J Clin Pharmacol 2007 47: 1129. [Abstract] [Full Text] [PDF]  

Pharmacokinetics and Pharmacodynamics:

Pamela A. Welch, Vikram P. Sinha, Ann L. Cleverly, Christelle Darstein, Shawn D. Flanagan, and Luna C. Musib
Safety, Tolerability, QTc Evaluation, and Pharmacokinetics of Single and Multiple Doses of Enzastaurin HCl (LY317615), a Protein Kinase C-ß Inhibitor, in Healthy Subjects
J Clin Pharmacol 2007 47: 1138. [Abstract] [Full Text] [PDF]  

Pharmacokinetics:

Gangadhar Sunkara, Ron Sabo, Yibin Wang, Yan-Ling He, Joelle Campestrini, Mitchell Rosenberg, Dan Howard, and William P. Dole
Dose Proportionality and the Effect of Food on Vildagliptin, a Novel Dipeptidyl Peptidase IV Inhibitor, in Healthy Volunteers
J Clin Pharmacol 2007 47: 1152. [Abstract] [Full Text] [PDF]  

Quantitative Clinical Pharmacology:

Hanna E. Silber, Petra M. Jauslin, Nicolas Frey, Ronald Gieschke, Ulrika S. H. Simonsson, and Mats O. Karlsson
An Integrated Model for Glucose and Insulin Regulation in Healthy Volunteers and Type 2 Diabetic Patients Following Intravenous Glucose Provocations
J Clin Pharmacol 2007 47: 1159. [Abstract] [Full Text] [PDF] [Appendix]  

Pediatrics:

Athena Zuppa, Sundararajan Vijayakumar, Bhuvana Jayaraman, Dimple Patel, Mahesh Narayan, Kalpana Vijayakumar, John T. Mondick, and Jeffrey S. Barrett
An Informatics Approach to Assess Pediatric Pharmacotherapy: Design and Implementation of a Hospital Drug Utilization System
J Clin Pharmacol 2007 47: 1172. [Abstract] [Full Text] [PDF]  

Letter to the Editor:

Toufigh Gordi
Comments on "Dual Effects of Rifampin on the Pharmacokinetics of Atrasentan"
J Clin Pharmacol 2007 47: 1181. [Full Text] [PDF]  

Hao Xiong and Robert A. Carr
Authors' Response
J Clin Pharmacol 2007 47: 1182. [Full Text] [PDF]  

ACCP Announcements:

Abstracts of the 36th Annual Meeting of the American College of Clinical Pharmacology, September 9-11, 2007, San Francisco, California
J Clin Pharmacol 2007 47: 1183. [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


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