Therapeutic Review:

Bruce E. Sands and Gilaad G. Kaplan

The Role of TNF in Ulcerative Colitis
J Clin Pharmacol 2007 47: 930. [Abstract] [Full Text] [PDF]  

Pharmacokinetics:

Raoul Bergner, Dirk M. Henrich, Martin Hoffmann, Andrea Honecker, Gerd Mikus, Bettina Nauth, Dietmar Nagel, and Michael Uppenkamp

Renal Safety and Pharmacokinetics of Ibandronate in Multiple Myeloma Patients With or Without Impaired Renal Function
J Clin Pharmacol 2007 47: 942. [Abstract] [Full Text] [PDF]  

Goutam C. Mistry, Elizabeth Migoya, Paul J. Deutsch, Gregory Winchell, Michael Hesney, Susan Li, Sheng Bi, Stacy Dilzer, Kenneth C. Lasseter, and Julie A. Stone

Single- and Multiple-Dose Administration of Caspofungin in Patients With Hepatic Insufficiency: Implications for Safety and Dosing Recommendations
J Clin Pharmacol 2007 47: 951. [Abstract] [Full Text] [PDF]  

Lester I. Harrison, Calvin Astry, Sandeep Kumar, and Carla Yunis

Pharmacokinetics of 852A, an Imidazoquinoline Toll-Like Receptor 7-Specific Agonist, Following Intravenous, Subcutaneous, and Oral Administrations in Humans
J Clin Pharmacol 2007 47: 962. [Abstract] [Full Text] [PDF]  

Ighovwerha Ofotokun, Susan K. Chuck, Jose N. Binongo, Mauricio Palau, Jeffrey L. Lennox, and Edward P. Acosta

Lopinavir/Ritonavir Pharmacokinetic Profile: Impact of Sex and Other Covariates Following a Change From Twice-Daily to Once-Daily Therapy
J Clin Pharmacol 2007 47: 970. [Abstract] [Full Text] [PDF]  

Pharmacokinetics and Pharmacodynamics:

Albert J. Azzaro, Chad M. VanDenBerg, John Ziemniak, Eva M. Kemper, Lawrence F. Blob, and Bryan J. Campbell

Evaluation of the Potential for Pharmacodynamic and Pharmacokinetic Drug Interactions Between Selegiline Transdermal System and Two Sympathomimetic Agents (Pseudoephedrine and Phenylpropanolamine) in Healthy Volunteers
J Clin Pharmacol 2007 47: 978. [Abstract] [Full Text] [PDF]  

Pharmacodynamics:

Bradley L. Urquhart, David J. Freeman, J. David Spence, and Andrew A. House

Mesna as a Nonvitamin Intervention to Lower Plasma Total Homocysteine Concentration: Implications for Assessment of the Homocysteine Theory of Atherosclerosis
J Clin Pharmacol 2007 47: 991. [Abstract] [Full Text] [PDF]  

Drug Interactions:

Yan-Ling He, Ron Sabo, Gangadhar Sunkara, Marie-Noëlle Bizot, Gilles-Jacques Riviere, Selene Leon, Monica Ligueros-Saylan, William P. Dole, and Dan Howard

Evaluation of Pharmacokinetic Interactions Between Vildagliptin and Digoxin in Healthy Volunteers
J Clin Pharmacol 2007 47: 998. [Abstract] [Full Text] [PDF]  

Robert Hermann, Werner Siegmund, Thomas Giessmann, Kristin Westphal, Anita Weinbrenner, Bernhard Hauns, Felix Reutter, Gezim Lahu, Karl Zech, and Thomas D. Bethke

The Oral, Once-Daily Phosphodiesterase 4 Inhibitor Roflumilast Lacks Relevant Pharmacokinetic Interactions With Inhaled Budesonide
J Clin Pharmacol 2007 47: 1005. [Abstract] [Full Text] [PDF]  

Quantitative Clinical Pharmacology:

Angelica Quartino, Mats O. Karlsson, Agneta Freijs, Niclas Jonsson, Peter Nygren, Jörgen Kristensen, Elin Lindhagen, and Rolf Larsson

Modeling of In Vitro Drug Activity and Prediction of Clinical Outcome in Acute Myeloid Leukemia
J Clin Pharmacol 2007 47: 1014. [Abstract] [Full Text] [PDF]  

Brief Reports/Clinical Studies:

René R. S. Packard, Susanna Schlegel, David Senouf, Fabienne Burger, Philippe Sigaud, Thomas Perneger, Claire-Anne Siegrist, and Franois Mach

Atorvastatin Treatment and Vaccination Efficacy
J Clin Pharmacol 2007 47: 1022. [Full Text] [PDF]  

Lawrence Rice, Marcie J. Hursting, G. Mark Baillie, and David A. McCollum

Argatroban Anticoagulation in Obese Versus Nonobese Patients: Implications for Treating Heparin-induced Thrombocytopenia
J Clin Pharmacol 2007 47: 1028. [Full Text] [PDF]  

Brief Report/Pharmacokinetics:

Richard Borrows, Gary Chusney, Marina Loucaidou, Anthony James, Shruti Goel, Sarah Borrows, Jen Van Tromp, Tom Cairns, Megan Griffith, Nadey Hakim, Adam McLean, Andrew Palmer, Vassilios Papalois, and David Taube

Analysis of Factors Influencing Tacrolimus Levels and Immunoassay Bias in Renal Transplantation
J Clin Pharmacol 2007 47: 1035. [Full Text] [PDF]  

Brief Report/Drug Interactions:

Matts Kågedal, Dag Nilsson, Gunilla Huledal, Ingalill Reinholdsson, Yi-Fang Cheng, Nils Åsenblad, David Pekar, and Olof Borgå

A Study of Organic Acid Transporter–Mediated Pharmacokinetic Interaction Between NXY-059 and Cefuroxime
J Clin Pharmacol 2007 47: 1043. [Full Text] [PDF]  

Brief Report/Pediatrics:

Ran D. Goldman, Michael Ong, Jacob Wolpin, John Doyle, Christopher Parshuram, and Gideon Koren

Pharmacological Risk Factors for Amphotericin B Nephrotoxicity in Children
J Clin Pharmacol 2007 47: 1049. [Full Text] [PDF]  

Highlights and Book Reviews:

Peter L. Bonate

Highlights and Book Reviews
J Clin Pharmacol 2007 47: 1055. [Full Text] [PDF]  

Errata:

Errata
J Clin Pharmacol 2007 47: 1061. [Full Text] [PDF]  

Errata
J Clin Pharmacol 2007 47: 1061. [Full Text] [PDF]  

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