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Contents: June 2007, Volume 47, Issue 6   [Index by Author] 
       Pharmacokinetics
       Pharmacokinetics and Pharmacodynamics
       Quantitative Clinical Pharmacology
       Meeting Review
       Drug Interactions
       Special Populations/Pediatrics
       Herbal Medicine
       Clinical Studies
       Therapeutic Review
 
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To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

Pharmacokinetics:

Taehyung Han, Jerold S. Harmatz, David J. Greenblatt, and J. A. Jeevendra Martyn
Fentanyl Clearance and Volume of Distribution Are Increased in Patients With Major Burns
J Clin Pharmacol 2007 47: 674. [Abstract] [Full Text] [PDF]  

Rajeev M. Menon, Mario A. González, Marijke H. Adams, Dwain S. Tolbert, Jocelyn H. Leu, and Eugenio A. Cefali
Effect of the Rate of Niacin Administration on the Plasma and Urine Pharmacokinetics of Niacin and Its Metabolites
J Clin Pharmacol 2007 47: 681. [Abstract] [Full Text] [PDF]  

Jerome J. Schentag, George Hill, Tom Chu, and Craig R. Rayner
Similarity in Pharmacokinetics of Oseltamivir and Oseltamivir Carboxylate in Japanese and Caucasian Subjects
J Clin Pharmacol 2007 47: 689. [Abstract] [Full Text] [PDF]  

Li Gong, Howard E. Greenberg, James L. Perhach, Scott A. Waldman, and Walter K. Kraft
The Pharmacokinetics of Taurolidine Metabolites in Healthy Volunteers
J Clin Pharmacol 2007 47: 697. [Abstract] [Full Text] [PDF]  

Kimberly E. Vanover, Doris Robbins-Weilert, Darren G. Wilbraham, Timothy G. K. Mant, Daniel P. van Kammen, Robert E. Davis, and David M. Weiner
Pharmacokinetics, Tolerability, and Safety of ACP-103 Following Single or Multiple Oral Dose Administration in Healthy Volunteers
J Clin Pharmacol 2007 47: 704. [Abstract] [Full Text] [PDF]  

Pharmacokinetics and Pharmacodynamics:

Bertold Renner, Geoff Clarke, Tim Grattan, Angelika Beisel, Christian Mueller, Ulrike Werner, Gerd Kobal, and Kay Brune
Caffeine Accelerates Absorption and Enhances the Analgesic Effect of Acetaminophen
J Clin Pharmacol 2007 47: 715. [Abstract] [Full Text] [PDF]  

Quantitative Clinical Pharmacology:

S. A. Van Wart, B. B. Cirincione, E. A. Ludwig, A. K. Meagher, J. M. Korth-Bradley, and J. S. Owen
Population Pharmacokinetics of Tigecycline in Healthy Volunteers
J Clin Pharmacol 2007 47: 727. [Abstract] [Full Text] [PDF]  

Meeting Review:

Rajesh Krishna, Hans Guenter Schaefer, and Ole J. Bjerrum
Effective Integration of Systems Biology, Biomarkers, Biosimulation, and Modeling in Streamlining Drug Development
J Clin Pharmacol 2007 47: 738. [Full Text] [PDF]  

Drug Interactions:

Anup K. Majumdar, Kerri X. Yan, Diana V. Selverian, Suna Barlas, Marvin Constanzer, James Dru, Jacqueline B. McCrea, Tuli Ahmed, Glen S. Frick, Walter K. Kraft, Kevin J. Petty, and Howard E. Greenberg
Effect of Aprepitant on the Pharmacokinetics of Intravenous Midazolam
J Clin Pharmacol 2007 47: 744. [Abstract] [Full Text] [PDF]  

M. Robert Blum, Gregory E. Chittick, John A. Begley, and Jian Zong
Steady-State Pharmacokinetics of Emtricitabine and Tenofovir Disoproxil Fumarate Administered Alone and in Combination in Healthy Volunteers
J Clin Pharmacol 2007 47: 751. [Abstract] [Full Text] [PDF]  

Special Populations/Pediatrics:

Declan Quinn, Twyla Bode, Joseph L. Reiz, Graeme A. E. Donnelly, and Andrew C. Darke
Single-Dose Pharmacokinetics of Multilayer-Release Methylphenidate and Immediate-Release Methylphenidate in Children With Attention-Deficit/Hyperactivity Disorder
J Clin Pharmacol 2007 47: 760. [Abstract] [Full Text] [PDF]  

Herbal Medicine:

Li Sun, Jinfang Shen, Xiaoyun Pang, Lungen Lu, Yimin Mao, and Minde Zeng
Phase I Safety and Pharmacokinetic Study of Magnesium Isoglycyrrhizinate After Single and Multiple Intravenous Doses in Chinese Healthy Volunteers
J Clin Pharmacol 2007 47: 767. [Abstract] [Full Text] [PDF] [Appendix]  

Clinical Studies:

Barbara Schütt, Michael Kunz, and Hartmut Blode
Coadministration of Estradiol/Drospirenone and Indomethacin Does Not Cause Hyperkalemia in Healthy Postmenopausal Women: A Randomized Open-Label Crossover Study
J Clin Pharmacol 2007 47: 774. [Abstract] [Full Text] [PDF]  

Therapeutic Review:

Hartmut Derendorf
Pharmacokinetic and Pharmacodynamic Properties of Inhaled Ciclesonide
J Clin Pharmacol 2007 47: 782. [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


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