ACCP Position Statement:

Joseph S. Bertino, Jr, Howard E. Greenberg, and Michael D. Reed

American College of Clinical Pharmacology Position Statement on the Use of Microdosing in the Drug Development Process
J Clin Pharmacol 2007 47: 418. [Full Text] [PDF]  

Drug Interactions:

Hao Xiong, Robert A. Carr, Charles S. Locke, David A. Katz, Ramanuj Achari, Thao T. Doan, Perry Wang, James R. Jankowski, and Darryl J. Sleep

Dual Effects of Rifampin on the Pharmacokinetics of Atrasentan
J Clin Pharmacol 2007 47: 423. [Abstract] [Full Text] [PDF]  

Pharmacokinetics:

Samit Hirawat, Ellen M. Welch, Gary L. Elfring, Valerie J. Northcutt, Sergey Paushkin, Seongwoo Hwang, Eileen M. Leonard, Neil G. Almstead, William Ju, Stuart W. Peltz, and Langdon L. Miller

Safety, Tolerability, and Pharmacokinetics of PTC124, a Nonaminoglycoside Nonsense Mutation Suppressor, Following Single- and Multiple-Dose Administration to Healthy Male and Female Adult Volunteers
J Clin Pharmacol 2007 47: 430. [Abstract] [Full Text] [PDF]  

Hideyasu Ishibashi, L. Creed Pettigrew, Yosuke Funakoshi, and Makoto Hiramatsu

Pharmacokinetics of Arundic Acid, an Astrocyte Modulating Agent, in Acute Ischemic Stroke
J Clin Pharmacol 2007 47: 445. [Abstract] [Full Text] [PDF]  

Sujata Vaidyanathan, Christine Reynolds, Ching-Ming Yeh, Marie-Noëlle Bizot, Hans Armin Dieterich, Dan Howard, and William P. Dole

Pharmacokinetics, Safety, and Tolerability of the Novel Oral Direct Renin Inhibitor Aliskiren in Elderly Healthy Subjects
J Clin Pharmacol 2007 47: 453. [Abstract] [Full Text] [PDF]  

James A. Dowell, Martin Stogniew, David Krause, and Bharat Damle

Anidulafungin Does Not Require Dosage Adjustment in Subjects With Varying Degrees of Hepatic or Renal Impairment
J Clin Pharmacol 2007 47: 461. [Abstract] [Full Text] [PDF]  

Gilbert Lefèvre, Greg Sedek, Hsun-Lun Aaron Huang, Marc Saltzman, Mitchell Rosenberg, Beate Kiese, and Peter Fordham

Pharmacokinetics of a Rivastigmine Transdermal Patch Formulation in Healthy Volunteers: Relative Effects of Body Site Application
J Clin Pharmacol 2007 47: 471. [Abstract] [Full Text] [PDF]  

Vanitha Sekar, Dries Kestens, Sabrina Spinosa-Guzman, Martine De Pauw, Els De Paepe, Tony Vangeneugden, Eric Lefebvre, and Richard M. W. Hoetelmans

The Effect of Different Meal Types on the Pharmacokinetics of Darunavir (TMC114)/Ritonavir in HIV-Negative Healthy Volunteers
J Clin Pharmacol 2007 47: 479. [Abstract] [Full Text] [PDF]  

Pharmacokinetics and Pharmacodynamics:

David J. Greenblatt, Jerold S. Harmatz, and Aziz Karim

Age and Gender Effects on the Pharmacokinetics and Pharmacodynamics of Ramelteon, a Hypnotic Agent Acting via Melatonin Receptors MT₁ and MT₂
J Clin Pharmacol 2007 47: 485. [Abstract] [Full Text] [PDF]  

Damayanthi Devineni, Donna Skee, Nicole Vaccaro, Joseph Massarella, Luc Janssens, Katherine D. LaGuardia, and Albert T. Leung

Pharmacokinetics and Pharmacodynamics of a Transdermal Contraceptive Patch and an Oral Contraceptive
J Clin Pharmacol 2007 47: 497. [Abstract] [Full Text] [PDF]  

Pediatrics:

Xiaoping Zhang, Tiffany Lin, Anne Bertasso, Claire Evans, Albert Dorr, Stanley J. Kolis, Miklos Salgo, Indravadan Patel on behalf of the T20-310/NV16056 Study Group

Population Pharmacokinetics of Enfuvirtide in HIV-1-Infected Pediatric Patients Over 48 Weeks of Treatment
J Clin Pharmacol 2007 47: 510. [Abstract] [Full Text] [PDF]  

Clinical Studies:

Hans J. Roethig, Barbara K. Zedler, Robin D. Kinser, Shixia Feng, Bettie L. Nelson, and Qiwei Liang

Short-Term Clinical Exposure Evaluation of a Second-Generation Electrically Heated Cigarette Smoking System
J Clin Pharmacol 2007 47: 518. [Abstract] [Full Text] [PDF]  

Highlights and Book Reviews:

Highlights and Book Reviews
J Clin Pharmacol 2007 47: 531. [Full Text] [PDF]  

Letter to the Editor:

Richard S. Blum

A Comment on "Grapefruit-Drug Interactions: Can Interactions With Drugs Be Avoided?"
J Clin Pharmacol 2007 47: 536. [Full Text] [PDF]  

Veronika Butterweck and Hartmut Derendorf

Response to Dr. Blum
J Clin Pharmacol 2007 47: 537. [Full Text] [PDF]  

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