Drug Interactions:

Albert J. Azzaro, John Ziemniak, Eva Kemper, Bryan J. Campbell, and Chad VanDenBerg

Selegiline Transdermal System: An Examination of the Potential for CYP450-Dependent Pharmacokinetic Interactions With 3 Psychotropic Medications
J Clin Pharmacol 2007 47: 146. [Abstract] [Full Text] [PDF]  

Goutam C. Mistry, Arthur J. Bergman, Wen-Lin Luo, Caroline Cilissen, Wouter Haazen, Michael J. Davies, Keith M. Gottesdiener, John A. Wagner, and Gary A. Herman

Multiple-Dose Administration of Sitagliptin, a Dipeptidyl Peptidase-4 Inhibitor, Does Not Alter the Single-Dose Pharmacokinetics of Rosiglitazone in Healthy Subjects
J Clin Pharmacol 2007 47: 159. [Abstract] [Full Text] [PDF]  

Rajesh Krishna, Arthur Bergman, Patrick Larson, Josee Cote, Kenneth Lasseter, Stacey Dilzer, Amy Wang, Wei Zeng, Li Chen, John Wagner, and Gary Herman

Effect of a Single Cyclosporine Dose on the Single-Dose Pharmacokinetics of Sitagliptin (MK-0431), a Dipeptidyl Peptidase-4 Inhibitor, in Healthy Male Subjects
J Clin Pharmacol 2007 47: 165. [Abstract] [Full Text] [PDF]  

Drug Metabolism:

Gemma L. Dickinson, Saeed Rezaee, Nicholas J. Proctor, Martin S. Lennard, Geoffrey T. Tucker, and Amin Rostami-Hodjegan

Incorporating In Vitro Information on Drug Metabolism Into Clinical Trial Simulations to Assess the Effect of CYP2D6 Polymorphism on Pharmacokinetics and Pharmacodynamics: Dextromethorphan as a Model Application
J Clin Pharmacol 2007 47: 175. [Abstract] [Full Text] [PDF]  

N. K. H. de Boer, L. J. J. Derijks, J. J. Keizer-Garritsen, L. H. J. Lambooy, W. Ruitenbeek, P. M. Hooymans, A. A. van Bodegraven, and D. J. de Jong

Extended Thiopurine Metabolite Assessment During 6-Thioguanine Therapy for Immunomodulation in Crohn's Disease
J Clin Pharmacol 2007 47: 187. [Abstract] [Full Text] [PDF]  

Pharmacokinetics:

Sujata Vaidyanathan, Vance Warren, ChingMing Yeh, Marie-Noelle Bizot, Hans Armin Dieterich, and William P. Dole

Pharmacokinetics, Safety, and Tolerability of the Oral Renin Inhibitor Aliskiren in Patients With Hepatic Impairment
J Clin Pharmacol 2007 47: 192. [Abstract] [Full Text] [PDF]  

Jennifer R. King, Thomas N. Kakuda, Sunita Paul, Man Ming Tse, Edward P. Acosta, and Stephen L. Becker

Pharmacokinetics of Saquinavir With Atazanavir or Low-Dose Ritonavir Administered Once Daily (ASPIRE I) or Twice Daily (ASPIRE II) in Seronegative Volunteers
J Clin Pharmacol 2007 47: 201. [Abstract] [Full Text] [PDF]  

Suzanne K. Swan, William B. Smith, Thomas C. Marbury, Mary Schumacher, Carolyn Dougherty, Bruce A. Mico, and Stephen A. Villano

Pharmacokinetics of Maribavir, a Novel Oral Anticytomegalovirus Agent, in Subjects With Varying Degrees of Renal Impairment
J Clin Pharmacol 2007 47: 209. [Abstract] [Full Text] [PDF]  

Pharmacokinetics and Pharmacodynamics:

Dagmar Kubitza, Michael Becka, Michael Zuehlsdorf, and Wolfgang Mueck

Body Weight Has Limited Influence on the Safety, Tolerability, Pharmacokinetics, or Pharmacodynamics of Rivaroxaban (BAY 59-7939) in Healthy Subjects
J Clin Pharmacol 2007 47: 218. [Abstract] [Full Text] [PDF]  

Biologics:

Lanyan Fang, Nicholas H. G. Holford, George Hinkle, Xianhua Cao, Jim J. Xiao, Mark Bloomston, Seth Gibbs, Osama Habib Al Saif, James T. Dalton, Kenneth K. Chan, Jeffery Schlom, Edward W. Martin, Jr, and Duxin Sun

Population Pharmacokinetics of Humanized Monoclonal Antibody HuCC49CH2 and Murine Antibody CC49 in Colorectal Cancer Patients
J Clin Pharmacol 2007 47: 227. [Abstract] [Full Text] [PDF]  

Quantitative Clinical Pharmacology:

Matthew M. Hutmacher, Ivan Nestorov, Tom Ludden, Ralph Zitnik, and Christopher Banfield

Modeling the Exposure-Response Relationship of Etanercept in the Treatment of Patients With Chronic Moderate to Severe Plaque Psoriasis
J Clin Pharmacol 2007 47: 238. [Abstract] [Full Text] [PDF]  

Herbal Medicine:

Sumeet R. Singh and Mitchell A. H. Levine

Potential Interactions Between Pharmaceuticals and Natural Health Products in Canada
J Clin Pharmacol 2007 47: 249. [Abstract] [Full Text] [PDF]  

Clinical Studies:

Shuichi Tsuruoka, Yasuhiko Kitoh, Atsuhiro Kawaguchi, Koh-ichi Sugimoto, Tokie Hayasaka, Tetsuo Saito, and Akio Fujimura

Clearance of Imidapril, an Angiotensin-Converting Enzyme Inhibitor, During Hemodialysis in Hypertensive Renal Failure Patients: Comparison With Quinapril and Enalapril
J Clin Pharmacol 2007 47: 259. [Abstract] [Full Text] [PDF]  

Dag Nilsson, Johan Wemer, Yi-Fang Cheng, Ingalill Reinholdsson, Gunnar Englund, Nils Egberg, and Sam Schulman

NXY-059 Does Not Affect Bleeding Time in Healthy Volunteers: A Randomized, Double-Blind, Placebo-Controlled, 3-Period Crossover Phase I Study
J Clin Pharmacol 2007 47: 264. [Abstract] [Full Text] [PDF]  

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