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Contents: December 2007, Volume 47, Issue 12   [Index by Author] 
       Pharmacokinetics/Special Populations
       Pharmacokinetics and Pharmacodynamics
       Pharmacodynamics
       Drug Interactions
       Clinical Trials
       Therapeutic Review
       Brief Report/Pharmacokinetics
       Highlights and Book Reviews
       Letter to the Editor
 
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To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.

Pharmacokinetics/Special Populations:

Nianhang Chen, Henry Lau, Linghui Kong, Gondi Kumar, Jerome B. Zeldis, Robert Knight, and Oscar L. Laskin
Pharmacokinetics of Lenalidomide in Subjects With Various Degrees of Renal Impairment and in Subjects on Hemodialysis
J Clin Pharmacol 2007 47: 1466. [Abstract] [Full Text] [PDF]  

Pharmacokinetics and Pharmacodynamics:

Dolly A. Parasrampuria, Kerri A. Schoedel, Reinhard Schuller, Joan Gu, Patrick Ciccone, Steven A. Silber, and Edward M. Sellers
Assessment of Pharmacokinetics and Pharmacodynamic Effects Related to Abuse Potential of a Unique Oral Osmotic-Controlled Extended-Release Methylphenidate Formulation in Humans
J Clin Pharmacol 2007 47: 1476. [Abstract] [Full Text] [PDF]  

Yuji Kumagai, Tomoe Fujita, Machiko Ozaki, Kunihiko Sahashi, Masayuki Ohkura, Tomoko Ohtsu, Yoshihiro Arai, Yusuke Sonehara, and Janet L. Nichol
Pharmacodynamics and Pharmacokinetics of AMG 531, a Thrombopoiesis-Stimulating Peptibody, in Healthy Japanese Subjects: A Randomized, Placebo-Controlled Study
J Clin Pharmacol 2007 47: 1489. [Abstract] [Full Text] [PDF]  

Susan E. Shoaf, Zhao Wang, Patricia Bricmont, and Suresh Mallikaarjun
Pharmacokinetics, Pharmacodynamics, and Safety of Tolvaptan, a Nonpeptide AVP Antagonist, During Ascending Single-Dose Studies in Healthy Subjects
J Clin Pharmacol 2007 47: 1498. [Abstract] [Full Text] [PDF]  

Shaker A. Mousa, Fuming Zhang, Ahmad Aljada, Seema Chaturvedi, Majde Takieddin, Haifeng Zhang, Lianli Chi, M. Cristina Castelli, Kristen Friedman, Michael M. Goldberg, and Robert J. Linhardt
Pharmacokinetics and Pharmacodynamics of Oral Heparin Solid Dosage Form in Healthy Human Subjects
J Clin Pharmacol 2007 47: 1508. [Abstract] [Full Text] [PDF]  

Pharmacodynamics:

Jules I. Schwartz, Chau Thach, Kenneth C. Lasseter, Jutta Miller, David Hreniuk, Deborah A. Hilliard, Karen M. Snyder, Barry J. Gertz, and Keith M. Gottesdiener
Effects of Etoricoxib and Comparator Nonsteroidal Anti-Inflammatory Drugs on Urinary Sodium Excretion, Blood Pressure, and Other Renal Function Indicators in Elderly Subjects Consuming a Controlled Sodium Diet
J Clin Pharmacol 2007 47: 1521. [Abstract] [Full Text] [PDF]  

Drug Interactions:

Karin Dilger, Richard Fux, Daniel Röck, Klaus Mörike, and Christoph H. Gleiter
Effect of High-Dose Metronidazole on Pharmacokinetics of Oral Budesonide and Vice Versa: A Double Drug Interaction Study
J Clin Pharmacol 2007 47: 1532. [Abstract] [Full Text] [PDF]  

Iftekhar Mahmood and Martin David Green
Drug Interaction Studies of Therapeutic Proteins or Monoclonal Antibodies
J Clin Pharmacol 2007 47: 1540. [Abstract] [Full Text] [PDF]  

Clinical Trials:

Richard A. Preston, Peter Harvey, Ottmar Herfert, Gary Dykstra, J. Wouter Jukema, Franklin Sun, and David Gillen
A Randomized, Placebo-Controlled Trial to Evaluate the Efficacy, Safety, and Pharmacodynamic Interaction of Coadministered Amlodipine and Atorvastatin in 1660 Patients With Concomitant Hypertension and Dyslipidemia: The Respond Trial
J Clin Pharmacol 2007 47: 1555. [Abstract] [Full Text] [PDF]  

Therapeutic Review:

David Warnke, Jason Barreto, and Zelalem Temesgen
Antiretroviral Drugs
J Clin Pharmacol 2007 47: 1570. [Abstract] [Full Text] [PDF]  

Brief Report/Pharmacokinetics:

Radu Constantinescu, Michael P. McDermott, Robert DiCenzo, Elisabeth A. de Blieck, H. Christopher Hyson, M. Flint Beal, Edward M. Bednarczyk, Mikhail Bogdanov, Linda J. Metakis, Susan E. Browne, Beverly J. Lorenzo, Bernard Ravina, and Karl Kieburtz
A Randomized Study of the Bioavailability of Different Formulations of Coenzyme Q10 (Ubiquinone)
J Clin Pharmacol 2007 47: 1580. [Full Text] [PDF]  

Highlights and Book Reviews:

Joan Korth-Bradley and K. R. Bhattacharjee
Highlights and Book Reviews
J Clin Pharmacol 2007 47: 1587. [Full Text] [PDF]  

Letter to the Editor:

Malcolm Rowland
Commentary on ACCP Position Statement on the Use of Microdosing in the Drug Development Process
J Clin Pharmacol 2007 47: 1595. [Full Text] [PDF]  

Joseph S. Bertino, Jr., Howard E. Greenberg, and Michael D. Reed
Response to Comments on ACCP Position Statement on Microdosing
J Clin Pharmacol 2007 47: 1597. [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


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