Pharmacokinetics:

Pamala Jacobson, Kathleen Green, John Rogosheske, Claudio Brunstein, Breta Ebeling, Todd DeFor, Philip McGlave, and Daniel Weisdorf

Highly Variable Mycophenolate Mofetil Bioavailability Following Nonmyeloablative Hematopoietic Cell Transplantation
J Clin Pharmacol 2007 47: 6. [Abstract] [Full Text] [PDF]  

Sarah D. McAleer, Oneeb Majid, Esther Venables, Torsten Polack, and Muhammed S. Sheikh

Pharmacokinetics and Safety of Ketorolac Following Single Intranasal and Intramuscular Administration in Healthy Volunteers
J Clin Pharmacol 2007 47: 13. [Abstract] [Full Text] [PDF]  

Peter H. Hinderling, Adel H. Karara, Ben Tao, Maria Pawula, Ian Wilding, and Ming Lu

Systemic Availability of the Active Metabolite Hydroxy-Fasudil After Administration of Fasudil to Different Sites of the Human Gastrointestinal Tract
J Clin Pharmacol 2007 47: 19. [Abstract] [Full Text] [PDF]  

Thomas D. Bethke, Gabriele M. Böhmer, Robert Hermann, Bernhard Hauns, Richard Fux, Klaus Mörike, Michael David, Dietrich Knoerzer, Wilhelm Wurst, and Christoph H. Gleiter

Dose-Proportional Intraindividual Single- and Repeated-Dose Pharmacokinetics of Roflumilast, an Oral, Once-Daily Phosphodiesterase 4 Inhibitor
J Clin Pharmacol 2007 47: 26. [Abstract] [Full Text] [PDF]  

Aziz Karim, Margaret Slater, Dawn Bradford, Lisa Schwartz, Zhen Zhao, Charlie Cao, and Aziz Laurent

Oral Antidiabetic Drugs: Bioavailability Assessment of Fixed-Dose Combination Tablets of Pioglitazone and Metformin. Effect of Body Weight, Gender, and Race on Systemic Exposures of Each Drug
J Clin Pharmacol 2007 47: 37. [Abstract] [Full Text] [PDF]  

Aziz Karim, Margaret Slater, Dawn Bradford, Lisa Schwartz, and Aziz Laurent

Oral Antidiabetic Drugs: Effect of Food on Absorption of Pioglitazone and Metformin From a Fixed-Dose Combination Tablet
J Clin Pharmacol 2007 47: 48. [Abstract] [Full Text] [PDF]  

Mona Darwish, Mary Kirby, Philmore Robertson, Jr, Edward Hellriegel, and John G. Jiang

Single-Dose and Steady-State Pharmacokinetics of Fentanyl Buccal Tablet in Healthy Volunteers
J Clin Pharmacol 2007 47: 56. [Abstract] [Full Text] [PDF]  

Dietrich Tuerck, Silke Appel-Dingemanse, Mojdeh Maboudian, Francoise Pommier, Yibin Wang, and Greg Sedek

Dose-Proportional Pharmacokinetics of d-threo-Methylphenidate After a Repeated-Action Release Dosage Form
J Clin Pharmacol 2007 47: 64. [Abstract] [Full Text] [PDF]  

Drug Interactions:

Heike Oberwittler, Andreas Hirschfeld-Warneken, Roland Wesch, Hans Willerich, Lenore Teichert, Karl-Heinz Lehr, Reinhard Ding, Walter Emil Haefeli, and Gerd Mikus

Significant Pharmacokinetic and Pharmacodynamic Interaction of Warfarin With the NO-Independent sGC Activator HMR1766
J Clin Pharmacol 2007 47: 70. [Abstract] [Full Text] [PDF]  

Pharmacogenomics:

Roshni P. Ramchandani, Yaning Wang, Brian P. Booth, Amna Ibrahim, John R. Johnson, Atiqur Rahman, Mehul Mehta, Federico Innocenti, Mark J. Ratain, and Jogarao V. S. Gobburu

The Role of SN-38 Exposure, UGT1A1^*28 Polymorphism, and Baseline Bilirubin Level in Predicting Severe Irinotecan Toxicity
J Clin Pharmacol 2007 47: 78. [Abstract] [Full Text] [PDF]  

Kyoung-Ah Kim, Pil-Whan Park, Ock-Je Lee, Dong-Kyun Kang, and Ji-Young Park

Effect of Polymorphic CYP3A5 Genotype on the Single-Dose Simvastatin Pharmacokinetics in Healthy Subjects
J Clin Pharmacol 2007 47: 87. [Abstract] [Full Text] [PDF]  

Pediatrics:

Anne Mannila, Elina Kumpulainen, Marko Lehtonen, Marja Heikkinen, Merja Laisalmi, Terhi Salo, Jarkko Rautio, Jouko Savolainen, and Hannu Kokki

Plasma and Cerebrospinal Fluid Concentrations of Indomethacin in Children After Intravenous Administration
J Clin Pharmacol 2007 47: 94. [Abstract] [Full Text] [PDF]  

Brian P. Booth, Atiqur Rahman, Ramzi Dagher, Donna Griebel, Shari Lennon, David Fuller, Chandra Sahajwalla, Mehul Mehta, and Jogarao V. S. Gobburu

Population Pharmacokinetic-Based Dosing of Intravenous Busulfan in Pediatric Patients
J Clin Pharmacol 2007 47: 101. [Abstract] [Full Text] [PDF]  

Clinical Studies:

Christoph Schindler, K. Bridget Brosnihan, Carlos M. Ferrario, Peter Bramlage, Ulf Maywald, Rainer Koch, Reinhard Oertel, and Wilhelm Kirch

Comparison of Inhibitory Effects of Irbesartan and Atorvastatin Treatment on the Renin Angiotensin System (RAS) in Veins: A Randomized Double-Blind Crossover Trial in Healthy Subjects
J Clin Pharmacol 2007 47: 112. [Abstract] [Full Text] [PDF]  

Jaime R. Gonzalez, Leopoldo Baiza-Duran, Juan Quintana-Hau, Ruben Tornero-Montaño, Gilberto Castaneda-Hernandez, Mario Ortiz, Felipe Alarcon-Oceguera, Marco Beltran-Loustaunau, Marco Cortez-Gastelum, Jorge Garcidueñas-Mejia, Pedro Gomez-Bastar, Jesus Jimenez-Roman, Vincent Korder-Ortega, Jose Paczka-Zapata, Marina Torres-Segura, and Gustavo Velasco-Gallegos

Comparison of the Stability, Efficacy, and Adverse Effect Profile of the Innovator 0.005% Latanoprost Ophthalmic Solution and a Novel Cyclodextrin-containing Formulation
J Clin Pharmacol 2007 47: 121. [Abstract] [Full Text] [PDF]  

Brief Reports/Clinical Studies:

Yan-Ling He, Anne Horowitz, Catherine E. Watson, James E. Foley, William Sallas, and Monica Ligueros-Saylan

Vildagliptin Does Not Affect C-Peptide Clearance in Patients With Type 2 Diabetes
J Clin Pharmacol 2007 47: 127. [Full Text] [PDF]  

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