Editorials:

Rajesh Krishna

Quantitative Clinical Pharmacology: Making Paradigm Shifts a Reality
J Clin Pharmacol 2006 46: 966. [Full Text] [PDF]  

Pharmacokinetics and Pharmacodynamics/Review:

Jaclyn M. LeBlanc, Joseph F. Dasta, Maria C. Pruchnicki, and Jerome J. Schentag

Impact of Disease States on the Pharmacokinetics and Pharmacodynamics of Angiotensin-Converting Enzyme Inhibitors
J Clin Pharmacol 2006 46: 968. [Abstract] [Full Text] [PDF]  

Pharmacokinetics and Pharmacodynamics:

Dagmar Kubitza, Michael Becka, Wolfgang Mueck, and Michael Zuehlsdorf

Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of Rivaroxaban—an Oral, Direct Factor Xa Inhibitor—Are Not Affected by Aspirin
J Clin Pharmacol 2006 46: 981. [Abstract] [Full Text] [PDF]  

Pharmacokinetics:

Hélène M. Faessel, Bill J. Smith, Megan A. Gibbs, Jason S. Gobey, David J. Clark, and Aaron H. Burstein

Single-Dose Pharmacokinetics of Varenicline, a Selective Nicotinic Receptor Partial Agonist, in Healthy Smokers and Nonsmokers
J Clin Pharmacol 2006 46: 991. [Abstract] [Full Text] [PDF]  

Pei Hu, Ji Jiang, Hongyun Wang, Keith Pietropaolo, George C. Chao, Nathaniel A. Brown, and Xiao-Jian Zhou

Single-Dose and Multiple-Dose Pharmacokinetics and Safety of Telbivudine After Oral Administration in Healthy Chinese Subjects
J Clin Pharmacol 2006 46: 999. [Abstract] [Full Text] [PDF]  

Peggy Gandia, Sylvie Saivin, Anne Pavy Le-Traon, Antonio Guell, and Georges Houin

Influence of Simulated Weightlessness on the Intramuscular and Oral Pharmacokinetics of Promethazine in 12 Human Volunteers
J Clin Pharmacol 2006 46: 1008. [Abstract] [Full Text] [PDF]  

S. Samuelsson, S. Johansson, S. Halldórsdóttir, H. Stenhoff, and K. P. Öhman

Food Does Not Affect the Pharmacokinetics of Tesaglitazar, a Novel Dual Peroxisome Proliferator-Activated Receptor / Agonist
J Clin Pharmacol 2006 46: 1017. [Abstract] [Full Text] [PDF]  

Mark J. Dresser, Dongwoo Kang, Peter Staehr, Shalini Gidwani, Cindy Guo, John P. Mulhall, and Nishit B. Modi

Pharmacokinetics of Dapoxetine, a New Treatment for Premature Ejaculation: Impact of Age and Effects of a High-Fat Meal
J Clin Pharmacol 2006 46: 1023. [Abstract] [Full Text] [PDF]  

Menger Chung, Albert Calcagni, Paul Glue, and Candace Bramson

Bioavailability of Amlodipine Besylate/Atorvastatin Calcium Combination Tablet
J Clin Pharmacol 2006 46: 1030. [Abstract] [Full Text] [PDF]  

Pediatrics:

Komathi Balakrishnan, Joanne Grieve, June Tordoff, Pauline Norris, and David Reith

Pediatric Licensing Status and the Availability of Suitable Formulations for New Medical Entities Approved in the United States Between 1998 and 2002
J Clin Pharmacol 2006 46: 1038. [Abstract] [Full Text] [PDF]  

Richard P. Malone, David S. Bennett, Mary Anne Delaney, Muniya S. Choudhury, James F. Luebbert, and Jacqueline Cater

Impersistence of Depression in Youth: Implications for Drug Study Design
J Clin Pharmacol 2006 46: 1044. [Abstract] [Full Text] [PDF]  

Highlights and Book Reviews:

Robert R. Bies

Highlights and Book Reviews
J Clin Pharmacol 2006 46: 1052. [Full Text] [PDF]  

Letter to the Editor:

Aristides Dokoumetzidis and Panos Macheras

A Comment on "Adverse Drug Reactions and Avalanches: Life at the Edge of Chaos"
J Clin Pharmacol 2006 46: 1057. [Full Text] [PDF]  

Daniel A. Frattarelli

Author's Response
J Clin Pharmacol 2006 46: 1059. [Full Text] [PDF]  

ACCP Announcements:

Abstracts Thirty-Fifth Annual Meeting American College of Clinical Pharmacology September 17-19, 2006 Cambridge, Massachusetts
J Clin Pharmacol 2006 46: 1061. [PDF]  

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