Forum:

Borje Darpo, Thierry Nebout, and Philip T. Sager

Clinical Evaluation of QT/QTc Prolongation and Proarrhythmic Potential for Nonantiarrhythmic Drugs: The International Conference on Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human Use E14 Guideline
J Clin Pharmacol 2006 46: 498. [Abstract] [Full Text] [PDF]  

Pediatrics:

David J. Edwards, Diane C. Chugani, Harry T. Chugani, Jamal Chehab, Monica Malian, and Jacob V. Aranda

Pharmacokinetics of Buspirone in Autistic Children
J Clin Pharmacol 2006 46: 508. [Abstract] [Full Text] [PDF]  

Pharmacogenomics:

Su-Jun Lee, William J. Jusko, Christine G. Salaita, Karim A. Calis, Michael W. Jann, Vicky E. Spratlin, Joyce A. Goldstein, and Yuen Yi Hon

Reduced Methylprednisolone Clearance Causing Prolonged Pharmacodynamics in a Healthy Subject Was Not Associated With CYP3A5*3 Allele or a Change in Diet Composition
J Clin Pharmacol 2006 46: 515. [Abstract] [Full Text] [PDF]  

Martha Sosa-Macías, Guillermo Elizondo, Carmen Flores-Pérez, Janet Flores-Pérez, Francisco Bradley-Alvarez, Ruth E. Alanis-Bañuelos, and Ismael Lares-Asseff

CYP2D6 Genotype and Phenotype in Amerindians of Tepehuano Origin and Mestizos of Durango, Mexico
J Clin Pharmacol 2006 46: 527. [Abstract] [Full Text] [PDF]  

Pharmacokinetics:

H. Kastrissios, S. Rohatagi, J. Moberly, K. Truitt, Y. Gao, R. Wada, M. Takahashi, K. Kawabata, and D. Salazar

Development of a Predictive Pharmacokinetic Model for a Novel Cyclooxygenase-2 Inhibitor
J Clin Pharmacol 2006 46: 537. [Abstract] [Full Text] [PDF]  

Pharmacokinetics and Pharmacodynamics:

Dagmar Kubitza, Michael Becka, Michael Zuehlsdorf, and Wolfgang Mueck

Effect of Food, an Antacid, and the H₂ Antagonist Ranitidine on the Absorption of BAY 59-7939 (Rivaroxaban), an Oral, Direct Factor Xa Inhibitor, in Healthy Subjects
J Clin Pharmacol 2006 46: 549. [Abstract] [Full Text] [PDF]  

Drug Interactions:

Srinivasan Ramanathan, Andrew Cheng, Angelique Mittan, Ramin Ebrahimi, and Brian P. Kearney

Absence of Clinically Relevant Pharmacokinetic Interaction Between Ribavirin and Tenofovir in Healthy Subjects
J Clin Pharmacol 2006 46: 559. [Abstract] [Full Text] [PDF]  

Leah M. Hesse, David J. Greenblatt, Lisa L. von Moltke, and Michael H. Court

Ritonavir Has Minimal Impact on the Pharmacokinetic Disposition of a Single Dose of Bupropion Administered to Human Volunteers
J Clin Pharmacol 2006 46: 567. [Abstract] [Full Text] [PDF]  

Brendan M. Johnson, Ivy H. Song, Kimberly K. Adkison, Julie Borland, Lei Fang, Yu Lou, M. Michelle Berrey, Anne N. Nafziger, Stephen C. Piscitelli, and Joseph S. Bertino, Jr

Evaluation of the Drug Interaction Potential of Aplaviroc, a Novel Human Immunodeficiency Virus Entry Inhibitor, Using a Modified Cooperstown 5 + 1 Cocktail
J Clin Pharmacol 2006 46: 577. [Abstract] [Full Text] [PDF]  

Brief Reports/Clinical Studies:

Waffaa N. Saieed, Iman A. AlPachachi, and Waleed M. Almashhadani

The Effect of Montelukast on Nasal Mucociliary Clearance
J Clin Pharmacol 2006 46: 588. [Full Text] [PDF]  

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