Commentary:

Richard S. Blum

Clinical Pharmacology of the Appeals and Exception Process: The Interface of the Patient, Physician, and Insurance Company to Assure Appropriate Care Under Medicare Part D
J Clin Pharmacol 2006 46: 394. [Abstract] [Full Text] [PDF]  

Huadong Tang and Michael Mayersohn

On the Observed Large Interspecies Overprediction of Human Clearance ("Vertical Allometry") of UCN-01: Further Support for a Proposed Model Based on Plasma Protein Binding
J Clin Pharmacol 2006 46: 398. [Abstract] [Full Text] [PDF]  

Forum:

Jamie Mihoko Doyle

What Race and Ethnicity Measure in Pharmacologic Research
J Clin Pharmacol 2006 46: 401. [Abstract] [Full Text] [PDF]  

Lea Harty, Keith Johnson, and Aidan Power

Race and Ethnicity in the Era of Emerging Pharmacogenomics
J Clin Pharmacol 2006 46: 405. [Abstract] [Full Text] [PDF]  

Pharmacogenomics:

Yuen Yi Hon, William J. Jusko, Vicky E. Spratlin, and Michael W. Jann

Altered Methylprednisolone Pharmacodynamics in Healthy Subjects With Histamine N-Methyltransferase C314T Genetic Polymorphism
J Clin Pharmacol 2006 46: 408. [Abstract] [Full Text] [PDF]  

Pharmacokinetics:

Shinichi Kawai, Hisayuki Sekino, Noriaki Yamashita, Shinichi Tsuchiwata, Hanjui Liu, and Joan M. Korth-Bradley

The Comparability of Etanercept Pharmacokinetics in Healthy Japanese and American Subjects
J Clin Pharmacol 2006 46: 418. [Abstract] [Full Text] [PDF]  

S. S. Jhee, A. S. Chappell, V. Zarotsky, S. V. Moran, M. Rosenthal, E. Kim, S. Chalon, N. Toublanc, J. Brandt, D. E. Coutant, and L. Ereshefsky

Multiple-Dose Plasma Pharmacokinetic and Safety Study of LY450108 and LY451395 (AMPA Receptor Potentiators) and Their Concentration in Cerebrospinal Fluid in Healthy Human Subjects
J Clin Pharmacol 2006 46: 424. [Abstract] [Full Text] [PDF]  

Pediatrics:

Ahmed El-Tahtawy, Hannu Kokki, and Bruce E. Reidenberg

Population Pharmacokinetics of Oxycodone in Children 6 Months to 7 Years Old
J Clin Pharmacol 2006 46: 433. [Abstract] [Full Text] [PDF]  

Jerry Goodisman and Abdul-Kader Souid

Constancy in Integrated Cisplatin Plasma Concentrations Among Pediatric Patients
J Clin Pharmacol 2006 46: 443. [Abstract] [Full Text] [PDF]  

Indulekha Warrier, Wei Du, Girija Natarajan, Vali Salari, and Jacob Aranda

Patterns of Drug Utilization in a Neonatal Intensive Care Unit
J Clin Pharmacol 2006 46: 449. [Abstract] [Full Text] [PDF]  

Methods:

B. Klem, G. Lappin, S. Nicholson, J. van de Wetering, D. E. de Vries, B. Oosterhuis, and R. C. Garner

Determination of the Bioavailability of [¹⁴C]-Hexaminolevulinate Using Accelerator Mass Spectrometry After Intravesical Administration to Human Volunteers
J Clin Pharmacol 2006 46: 456. [Abstract] [Full Text] [PDF]  

Clinical Studies:

Ruediger Nave, Mark A. Wingertzahn, Sheldon Brookman, Shigenori Kaida, and Takashi Matsunaga

Safety, Tolerability, and Exposure of Ciclesonide Nasal Spray in Healthy and Asymptomatic Subjects With Seasonal Allergic Rhinitis
J Clin Pharmacol 2006 46: 461. [Abstract] [Full Text] [PDF]  

Nicole Kotzailias, Toni Andonovski, Alexander Dukic, Victor L. Serebruany, and Bernd Jilma

Antiplatelet Activity During Coadministration of the Selective Serotonin Reuptake Inhibitor Paroxetine and Aspirin in Male Smokers: A Randomized, Placebo-Controlled, Double-blind Trial
J Clin Pharmacol 2006 46: 468. [Abstract] [Full Text] [PDF]  

William A. Bauman, Steven C. Kirshblum, Nancy G. Morrison, Christopher M. Cirnigliaro, Run-Lin Zhang, and Ann M. Spungen

Effect of Low-Dose Baclofen Administration on Plasma Insulin-like Growth Factor-I in Persons With Spinal Cord Injury
J Clin Pharmacol 2006 46: 476. [Abstract] [Full Text] [PDF]  

Brief Reports/Clinical Studies:

I. M. Twiss, A. H. M. van den Berk, M. L. de Kam, J. J. Bosch, A. F. Cohen, P. Vermeij, and J. Burggraaf

A Comparison of the Gastrointestinal Effects of the Nitrogen-Containing Bisphosphonates Pamidronate, Alendronate, and Olpadronate in Humans
J Clin Pharmacol 2006 46: 483. [Full Text] [PDF]  

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