Drug Interactions:

S. U. Mertens-Talcott, I. Zadezensky, W. V. De Castro, H. Derendorf, and V. Butterweck

Grapefruit-Drug Interactions: Can Interactions With Drugs Be Avoided?
J Clin Pharmacol 2006 46: 1390. [Abstract] [Full Text] [PDF]  

Stig Strid, Dag Nilsson, Olof Borgå, Johan Wemer, and Anders Grahnén

NXY-059 Does Not Significantly Interact With Furosemide in Healthy Volunteers
J Clin Pharmacol 2006 46: 1417. [Abstract] [Full Text] [PDF]  

Drug Metabolism:

Robert L. Walsky, Angela V. Astuccio, and R. Scott Obach

Evaluation of 227 Drugs for In Vitro Inhibition of Cytochrome P450 2B6
J Clin Pharmacol 2006 46: 1426. [Abstract] [Full Text] [PDF]  

Pharmacokinetics:

Hélène M. Faessel, Megan A. Gibbs, David J. Clark, Kevin Rohrbacher, Marilyn Stolar, and Aaron H. Burstein

Multiple-Dose Pharmacokinetics of the Selective Nicotinic Receptor Partial Agonist, Varenicline, in Healthy Smokers
J Clin Pharmacol 2006 46: 1439. [Abstract] [Full Text] [PDF]  

Minghong Jia, Bonnie Coats, Monisha Chadha, Barbara Frentzen, Javier Perez-Rodriguez, Paul A. Chadik, Richard A. Yost, George N. Henderson, and Peter W. Stacpoole

Human Kinetics of Orally and Intravenously Administered Low-Dose 1,2-¹³C-Dichloroacetate
J Clin Pharmacol 2006 46: 1449. [Abstract] [Full Text] [PDF]  

B. Gillespie, P. Zia-Amirhosseini, M. Salfi, T. Kakkar, J. Wang, S. Gupta, B. Smith, R. Robson, and J. T. Sullivan

Effect of Renal Function on the Pharmacokinetics of Palifermin
J Clin Pharmacol 2006 46: 1460. [Abstract] [Full Text] [PDF]  

Pharmacokinetics and Pharmacodynamics:

David J. Greenblatt, Eric Legangneux, Jerold S. Harmatz, Estelle Weinling, Jon Freeman, Kathleen Rice, and Gary K. Zammit

Dynamics and Kinetics of a Modified-Release Formulation of Zolpidem: Comparison With Immediate-Release Standard Zolpidem and Placebo
J Clin Pharmacol 2006 46: 1469. [Abstract] [Full Text] [PDF]  

Clinical Studies:

Ryan M. Carnahan, Brian C. Lund, Paul J. Perry, Bruce G. Pollock, and Kennith R. Culp

The Anticholinergic Drug Scale as a Measure of Drug-Related Anticholinergic Burden: Associations With Serum Anticholinergic Activity
J Clin Pharmacol 2006 46: 1481. [Abstract] [Full Text] [PDF] [Appendix]  

Therapeutic Review:

Johanna P. Daily

Antimalarial Drug Therapy: The Role of Parasite Biology and Drug Resistance
J Clin Pharmacol 2006 46: 1487. [Abstract] [Full Text] [PDF]  

Highlights and Book Reviews:

Kearney PM, Baigent C, Godwin J, Halls H, Emberson JR, Patrano C. Do selective cyclo-oxygenase-2 inhibitors and traditional non-steroidal anti-inflammatory drugs increase the risk of atherothrombosis? Meta-analysis of randomised trials. BMJ. 2006;332:1302-1308.
J Clin Pharmacol 2006 46: 1498. [Full Text] [PDF]  

Special Issue on Medical Imaging in Oncology, Journal of Clinical Oncology, July 10, 2006
J Clin Pharmacol 2006 46: 1498. [Full Text] [PDF]  

Kearney PM, Baigent C, Godwin J, Halls H, Emberson JR, Patrano C. Do selective cyclo-oxygenase-2 inhibitors and traditional non-steroidal anti-inflammatory drugs increase the risk of atherothrombosis? Meta-analysis of randomised trials. BMJ. 2006;332:1302-1308.
J Clin Pharmacol 2006 46: 1498. [Full Text] [PDF]  

Ghibellini G, Leslie EM, Brouwer KL. Methods to evaluate biliary excretion of drugs in humans: an updated review. Mol Pharmacol. 2006;3:198-211.
J Clin Pharmacol 2006 46: 1499. [Full Text] [PDF]  

Suntharalingam G, Perry MR, Ward S, et al. Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412. N Engl J Med. 2006;355:1-11.
J Clin Pharmacol 2006 46: 1499. [Full Text] [PDF]  

Krishna R, ed. Dose Optimization in Drug Development. New York: Taylor & Francis; 2006. Ting N, ed. Dose Finding in Drug Development. New York: Springer; 2006.
J Clin Pharmacol 2006 46: 1500. [Full Text] [PDF]  

BOOKS AVAILABLE FOR REVIEW
J Clin Pharmacol 2006 46: 1500. [Full Text] [PDF]  

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