Pharmacokinetics:

Aaron H. Burstein, Terence Fullerton, David J. Clark, and Hélène M. Faessel

Pharmacokinetics, Safety, and Tolerability After Single and Multiple Oral Doses of Varenicline in Elderly Smokers
J Clin Pharmacol 2006 46: 1234. [Abstract] [Full Text] [PDF]  

Bharat Damle, Dial Hewlett, Jr, Poe-Hirr Hsyu, Mark Becker, and Annkatrin Petersen

Pharmacokinetics of Nelfinavir in Subjects With Hepatic Impairment
J Clin Pharmacol 2006 46: 1241. [Abstract] [Full Text] [PDF]  

Jing-He Yan, Marc Bifano, Steven Olsen, Robert A. Smith, Duxi Zhang, Dennis M. Grasela, and Frank LaCreta

Entecavir Pharmacokinetics, Safety, and Tolerability After Multiple Ascending Doses in Healthy Subjects
J Clin Pharmacol 2006 46: 1250. [Abstract] [Full Text] [PDF]  

Mette Maja B. Teigen, Stephen Duffull, Lily Dang, and David W. Johnson

Dosing of Gentamicin in Patients With End-Stage Renal Disease Receiving Hemodialysis
J Clin Pharmacol 2006 46: 1259. [Abstract] [Full Text] [PDF]  

Drug Interactions:

Honghui Zhou

Population-Based Assessments of Clinical Drug-Drug Interactions: Qualitative Indices or Quantitative Measures?
J Clin Pharmacol 2006 46: 1268. [Abstract] [Full Text] [PDF]  

Shinya Uchida, Hiroshi Yamada, Xiao Dong Li, Shuji Maruyama, Yuki Ohmori, Tomomi Oki, Hiroshi Watanabe, Keizo Umegaki, Kyoichi Ohashi, and Shizuo Yamada

Effects of Ginkgo Biloba Extract on Pharmacokinetics and Pharmacodynamics of Tolbutamide and Midazolam in Healthy Volunteers
J Clin Pharmacol 2006 46: 1290. [Abstract] [Full Text] [PDF]  

Drug Metabolism:

Mary Beth O'Connell, Reginald F. Frye, Gary R. Matzke, John V. St. Peter, Laurie A. Willhite, Margaret R. Welch, Paul Kowal, and June LaValleur

Effect of Conjugated Equine Estrogens on Oxidative Metabolism in Middle-aged and Elderly Postmenopausal Women
J Clin Pharmacol 2006 46: 1299. [Abstract] [Full Text] [PDF]  

Randy C. Dockens, Daniel E. Salazar, I. Edgar Fulmor, Michele Wehling, Mark E. Arnold, and Robert Croop

Pharmacokinetics of a Newly Identified Active Metabolite of Buspirone After Administration of Buspirone Over Its Therapeutic Dose Range
J Clin Pharmacol 2006 46: 1308. [Abstract] [Full Text] [PDF]  

Methods:

Brian Kirby, Evan D. Kharasch, Kenneth T. Thummel, Vishal S. Narang, Christine J. Hoffer, and Jashvant D. Unadkat

Simultaneous Measurement of In Vivo P-glycoprotein and Cytochrome P450 3A Activities
J Clin Pharmacol 2006 46: 1313. [Abstract] [Full Text] [PDF]  

Clinical Studies:

Jenny E. Kootstra-Ros, Marga J. M. Van Weelden, John W. J. Hinrichs, Peter A. G. M. De Smet, and Jan van der Weide

Therapeutic Drug Monitoring of Antidepressants and Cytochrome P450 Genotyping in General Practice
J Clin Pharmacol 2006 46: 1320. [Abstract] [Full Text] [PDF]  

Josiane Cristófani Poggi, Giuliano Rodrigo Barissa, Eduardo Antônio Donadi, Milton Cesar Foss, Fernando de Queiróz Cunha, Vera Lucia Lanchote, and Marina Lemos dos Reis

Pharmacodynamics, Chiral Pharmacokinetics, and Pharmacokinetic-Pharmacodynamic Modeling of Fenoprofen in Patients With Diabetes Mellitus
J Clin Pharmacol 2006 46: 1328. [Abstract] [Full Text] [PDF]  

Michael S. Kostapanos, Haralampos J. Milionis, Irene Gazi, Christine Kostara, Eleni T. Bairaktari, and Moses Elisaf

Rosuvastatin Increases -1 Microglobulin Urinary Excretion in Patients With Primary Dyslipidemia
J Clin Pharmacol 2006 46: 1337. [Abstract] [Full Text] [PDF]  

Noriko Daneshtalab, Richard Z. Lewanczuk, Anthony S. Russell, and Fakhreddin Jamali

Drug-Disease Interactions: Losartan Effect Is Not Downregulated by Rheumatoid Arthritis
J Clin Pharmacol 2006 46: 1344. [Abstract] [Full Text] [PDF]  

Pharmacogenomics:

Ping He, Michael H. Court, David J. Greenblatt, and Lisa L. von Moltke

Human Pregnane X Receptor: Genetic Polymorphisms, Alternative mRNA Splice Variants, and Cytochrome P450 3A Metabolic Activity
J Clin Pharmacol 2006 46: 1356. [Abstract] [Full Text] [PDF]  

Herbal Medicine:

Xuemin Jiang, Elaine Y. L. Blair, and Andrew J. McLachlan

Investigation of the Effects of Herbal Medicines on Warfarin Response in Healthy Subjects: A Population Pharmacokinetic-Pharmacodynamic Modeling Approach
J Clin Pharmacol 2006 46: 1370. [Abstract] [Full Text] [PDF]  

Letter to the Editor:

Susannah L. Kenyon, Jennifer Button, Paolo Perella, Denise A. McKeown, and David W. Holt

An Herbal Remedy for Impotence: More Than Was Bargained For
J Clin Pharmacol 2006 46: 1379. [Full Text] [PDF]  

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