Education Series:

Stephen P. Glasser and George Howard

Clinical Trial Design Issues: At Least 10 Things You Should Look For in Clinical Trials
J Clin Pharmacol 2006 46: 1106. [Abstract] [Full Text] [PDF]  

Pharmacokinetics:

Steven Zhang, Peter Zannikos, Ahmad Awada, Martine Piccart-Gebhart, Luc Y. Dirix, Pierre Fumoleau, Tom Verhaeghe, Marc Francois, and Peter De Porre

Pharmacokinetics of Tipifarnib After Oral and Intravenous Administration in Subjects With Advanced Cancer
J Clin Pharmacol 2006 46: 1116. [Abstract] [Full Text] [PDF]  

Goutam C. Mistry, Anup K. Majumdar, Suzanne Swan, Domenic Sica, Alison Fisher, Yang Xu, Michael Hesney, Liwen Xi, John A. Wagner, and Paul J. Deutsch

Pharmacokinetics of Ertapenem in Patients With Varying Degrees of Renal Insufficiency and in Patients on Hemodialysis
J Clin Pharmacol 2006 46: 1128. [Abstract] [Full Text] [PDF]  

Ajit Shah, Timothy DeGroot, and Glen Apseloff

Pharmacokinetic Evaluation and Safety Profile of a 15-Minute Versus 30-Second Infusion of Palonosetron in Healthy Subjects
J Clin Pharmacol 2006 46: 1139. [Abstract] [Full Text] [PDF]  

Bernhard Hauns, Robert Hermann, Andreas Hünnemeyer, Rolf Herzog, Dieter Hauschke, Karl Zech, and Thomas D. Bethke

Investigation of a Potential Food Effect on the Pharmacokinetics of Roflumilast, an Oral, Once-Daily Phosphodiesterase 4 Inhibitor, in Healthy Subjects
J Clin Pharmacol 2006 46: 1146. [Abstract] [Full Text] [PDF]  

Xin Zhang, Brian R. Overholser, Michael B. Kays, and Kevin M. Sowinski

Gatifloxacin Pharmacokinetics in Healthy Men and Women
J Clin Pharmacol 2006 46: 1154. [Abstract] [Full Text] [PDF]  

Marcus A. Bain, Robert W. Milne, and Allan M. Evans

Disposition and Metabolite Kinetics of Oral L-carnitine in Humans
J Clin Pharmacol 2006 46: 1163. [Abstract] [Full Text] [PDF]  

Chonghua Li, Joseph L. Kuti, Charles H. Nightingale, and David P. Nicolau

Population Pharmacokinetic Analysis and Dosing Regimen Optimization of Meropenem in Adult Patients
J Clin Pharmacol 2006 46: 1171. [Abstract] [Full Text] [PDF]  

Drug Interactions:

Danny Soon, Prajakti A. Kothare, Helle Linnebjerg, Soomin Park, Eunice Yuen, Kenneth F. Mace, and Stephen D. Wise

Effect of Exenatide on the Pharmacokinetics and Pharmacodynamics of Warfarin in Healthy Asian Men
J Clin Pharmacol 2006 46: 1179. [Abstract] [Full Text] [PDF]  

A. Portolés, A. Terleira, A. Calvo, I. Martínez, and G. Resplandy

Effects of Hypericum perforatum on Ivabradine Pharmacokinetics in Healthy Volunteers: An Open-Label, Pharmacokinetic Interaction Clinical Trial
J Clin Pharmacol 2006 46: 1188. [Abstract] [Full Text] [PDF]  

A. Portolés, A. Calvo, A. Terleira, L. Laredo, G. Resplandy, C. Gorostiaga, and A. Moreno

Lack of Pharmacokinetic Interaction Between Omeprazole or Lansoprazole and Ivabradine in Healthy Volunteers: An Open-Label, Randomized, Crossover, Pharmacokinetic Interaction Clinical Trial
J Clin Pharmacol 2006 46: 1195. [Abstract] [Full Text] [PDF]  

Pediatrics:

Ole Østerberg, Radojka M. Savic, Mats O. Karlsson, Ulrika S. H. Simonsson, Jens Peter Nørgaard, Johan Vande Walle, and Henrik Agersø

Pharmacokinetics of Desmopressin Administrated as an Oral Lyophilisate Dosage Form in Children With Primary Nocturnal Enuresis and Healthy Adults
J Clin Pharmacol 2006 46: 1204. [Abstract] [Full Text] [PDF]  

Brief Reports/Pharmacokinetics:

Menger Chung, Albert Calcagni, Paul Glue, and Candace Bramson

Effect of Food on the Bioavailability of Amlodipine Besylate/Atorvastatin Calcium Combination Tablet
J Clin Pharmacol 2006 46: 1212. [Full Text] [PDF]  

Dusan Jovanovic, Slavko Cusic, Dragana Rancic, Danica Srnic, and Natasa Perkovic-Vukcevic

A Pharmacokinetic Comparison of Generic Tablets Containing Bisoprolol With the Innovator Formulation in Healthy Volunteers
J Clin Pharmacol 2006 46: 1217. [Full Text] [PDF]  

Errata:

Erratum
J Clin Pharmacol 2006 46: 1225. [Full Text] [PDF]  

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