Pharmacokinetics:

Anne C. Hermann, Anne N. Nafziger, Jennifer Victory, Robert Kulawy, Mario L. Rocci, Jr, and Joseph S. Bertino, Jr

Over-the-Counter Progesterone Cream Produces Significant Drug Exposure Compared to a Food and Drug Administration–Approved Oral Progesterone Product
J Clin Pharmacol 2005 45: 614. [Abstract] [Full Text] [PDF]  

Jeffrey J. Miceli, Keith D. Wilner, Suzanne K. Swan, MD, and Thomas G. Tensfeldt

Pharmacokinetics, Safety, and Tolerability of Intramuscular Ziprasidone in Healthy Volunteers
J Clin Pharmacol 2005 45: 620. [Abstract] [Full Text] [PDF]  

Pharmacokinetics and Pharmacodynamics:

Venkatesh Atul Bhattaram, Nelamangala V. Nagaraja, Tanja Peters, Thomas Machnig, Sonja Kroesser, Andreas Kovar, and Hartmut Derendorf

Population Pharmacokinetics of Eniporide and Its Metabolite in Healthy Subjects and Patients With Acute Myocardial Infarction
J Clin Pharmacol 2005 45: 631. [Abstract] [Full Text] [PDF]  

Clinical Studies:

David W. Wright, James C. Ritchie, Richard E. Mullins, Arthur L. Kellermann, and Donald D. Denson

Steady-State Serum Concentrations of Progesterone Following Continuous Intravenous Infusion in Patients With Acute Moderate to Severe Traumatic Brain Injury
J Clin Pharmacol 2005 45: 640. [Abstract] [Full Text] [PDF]  

Caroline Trudeau, Monette M. Cotreau, Lucille Stonis, Kevin H. Dykstra, Judy L. Oestreicher, Andrew Strahs, Andrew J. Dorner, Victor H. Van Cleave, William L. Trepicchio, and Ullrich S. Schwertschlag

A Single Administration of Recombinant Human Interleukin-12 Is Associated With Increased Expression Levels of Interferon-gamma and Signal Transducer and Activator of Transcription in Healthy Subjects
J Clin Pharmacol 2005 45: 649. [Abstract] [Full Text] [PDF]  

Olaf Burkhardt, Jolanta Majcher-Peszynska, Klaus Borner, Ralf Mundkowski, Bernd Drewelow, Hartmut Derendorf, and Tobias Welte

Penetration of Ertapenem Into Different Pulmonary Compartments of Patients Undergoing Lung Surgery
J Clin Pharmacol 2005 45: 659. [Abstract] [Full Text] [PDF]  

Drug Metabolism:

Shanshan Liu, Reginald F. Frye, Robert A. Branch, Raman Venkataramanan, John J. Fung, and Gilbert J. Burckart

Effect of Age and Postoperative Time on Cytochrome P450 Enzyme Activity Following Liver Transplantation
J Clin Pharmacol 2005 45: 666. [Abstract] [Full Text] [PDF]  

Pharmacogenomics:

Miki Nakajima, Yuto Fujiki, Satoru Kyo, Taro Kanaya, Mitsuhiro Nakamura, Yoshiko Maida, Masaaki Tanaka, Masaki Inoue, and Tsuyoshi Yokoi

Pharmacokinetics of Paclitaxel in Ovarian Cancer Patients and Genetic Polymorphisms of CYP2C8, CYP3A4, and MDR1
J Clin Pharmacol 2005 45: 674. [Abstract] [Full Text] [PDF]  

Herbal Medicine:

Karin Woelkart, Christoph Koidl, Andrea Grisold, J. David Gangemi, Ronald B. Turner, Egon Marth, and Rudolf Bauer

Bioavailability and Pharmacokinetics of Alkamides From the Roots of Echinacea angustifolia in Humans
J Clin Pharmacol 2005 45: 683. [Abstract] [Full Text] [PDF]  

Brief Reports/Pharmacokinetics:

Tsukasa Uno, Norio Yasui-Furukori, Takenori Takahata, Kazunobu Sugawara, and Tomonori Tateishi

Lack of Significant Effect of Grapefruit Juice on the Pharmacokinetics of Lansoprazole and Its Metabolites in Subjects With Different CYP2C19 Genotypes
J Clin Pharmacol 2005 45: 690. [Full Text]  

Menger Chung, Dahlia Garza, Michael Gaffney, and Paul Glue

Bioavailability of Amlodipine Besylate Following Oral Administration as a Tablet Dispersed in Applesauce
J Clin Pharmacol 2005 45: 695. [Full Text]  

Brief Report/Drug Interactions:

Gregory A. Winchell, Goutam C. Mistry, Prasad P. Kari, Thomas Marbury, Jutta L. Miller, Richard C. Simpson, A. David Rodrigues, Keith M. Gottesdiener, and John A. Wagner

The Effect of Ketoconazole on the Pharmacokinetics of a Selective _1A-Adrenoceptor Antagonist
J Clin Pharmacol 2005 45: 699. [Full Text] [PDF]  

Brief Reports/Clinical Studies:

Martín J. García-González, Alberto Domínguez-Rodríguez, and Julio J. Ferrer-Hita

Utility of Levosimendan, a New Calcium Sensitizing Agent, in the Treatment of Cardiogenic Shock Due to Myocardial Stunning in Patients With ST-Elevation Myocardial Infarction: A Series of Cases
J Clin Pharmacol 2005 45: 704. [Full Text] [PDF]  

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