Therapeutic Review:

Steven G. Chrysant and George S. Chrysant

Pharmacological and Clinical Profile of Moexipril: A Concise Review
J Clin Pharmacol 2004 44: 827. [Abstract] [Full Text] [PDF]  

Special Review:

Annemarie Graebe, Edgar L. Schuck, Petra Lensing, Lakshmi Putcha, and Hartmut Derendorf

Physiological, Pharmacokinetic, and Pharmacodynamic Changes in Space
J Clin Pharmacol 2004 44: 837. [Abstract] [Full Text] [PDF]  

Pharmacogenetics:

Luca Paoluzzi, Arun S. Singh, Douglas K. Price, Romano Danesi, Ron H. J. Mathijssen, Jaap Verweij, William D. Figg, and Alex Sparreboom

Influence of Genetic Variants in UGT1A1 and UGT1A9 on the In Vivo Glucuronidation of SN-38
J Clin Pharmacol 2004 44: 854. [Abstract] [Full Text] [PDF]  

Pharmacoepidemiology:

David Lehmann, Jamie Nelsen, Vijay Ramanath, Nancy Newman, David Duggan, and Adrienne Smith

Lack of Attenuation in the Antitumor Effect of Tamoxifen by Chronic CYP Isoform Inhibition
J Clin Pharmacol 2004 44: 861. [Abstract] [Full Text] [PDF]  

Pediatrics:

Rubén Burgos-Vargas, Ivan Foeldvari, Angelika Thon, Ronald Linke, and Dietrich Tuerck

Pharmacokinetics of Meloxicam in Patients With Juvenile Rheumatoid Arthritis
J Clin Pharmacol 2004 44: 866. [Abstract] [Full Text] [PDF]  

Mary Buckwalter, James A. Dowell, Joan Korth-Bradley, Boris Gorovits, and Philip R. Mayer

Pharmacokinetics of Gemtuzumab Ozogamicin as a Single-Agent Treatment of Pediatric Patients With Refractory or Relapsed Acute Myeloid Leukemia
J Clin Pharmacol 2004 44: 873. [Abstract] [Full Text] [PDF]  

Clinical Studies:

XingXiang Wang, JunHui Zhu, JunZhu Chen, and YunPeng Shang

Effects of Nicotine on the Number and Activity of Circulating Endothelial Progenitor Cells
J Clin Pharmacol 2004 44: 881. [Abstract] [Full Text] [PDF]  

Pharmacokinetics and Pharmacodynamics:

Manabu Tashiro, Yumiko Sakurada, Kentaro Iwabuchi, Hideki Mochizuki, Motohisa Kato, Mariko Aoki, Yoshihito Funaki, Masatoshi Itoh, Ren Iwata, Dean F. Wong, and Kazuhiko Yanai

Central Effects of Fexofenadine and Cetirizine: Measurement of Psychomotor Performance, Subjective Sleepiness, and Brain Histamine H₁-Receptor Occupancy Using ¹¹C-Doxepin Positron Emission Tomography
J Clin Pharmacol 2004 44: 890. [Abstract] [Full Text] [PDF]  

Gary T. Emmons, Rick Argenti, Louis L. Martin, Nancy E. Martin, and Bradford K. Jensen

Pharmacokinetics of M100240 and MDL 100,173, a Dual Angiotensin-Converting Enzyme/Neutral Endopeptidase Inhibitor, in Healthy Young and Elderly Volunteers
J Clin Pharmacol 2004 44: 901. [Abstract] [Full Text] [PDF]  

Luis Almeida and Patrício Soares-da-Silva

Safety, Tolerability, and Pharmacokinetic Profile of BIA 2-093, a Novel Putative Antiepileptic, in a Rising Multiple-Dose Study in Young Healthy Humans
J Clin Pharmacol 2004 44: 906. [Abstract] [Full Text] [PDF]  

Drug Interactions:

Chetan S. Karyekar, Natalie D. Eddington, Andrew Briglia, Paul O. Gubbins, and Thomas C. Dowling

Renal Interaction Between Itraconazole and Cimetidine
J Clin Pharmacol 2004 44: 919. [Abstract] [Full Text] [PDF]  

Troy C. Sarich, Kajs-Marie Schützer, Hassan Dorani, Ulrika Wall, Inge Kalies, Lis Ohlsson, and Ulf G. Eriksson

No Pharmacokinetic or Pharmacodynamic Interaction Between Atorvastatin and the Oral Direct Thrombin Inhibitor Ximelagatran
J Clin Pharmacol 2004 44: 928. [Abstract] [Full Text] [PDF]  

Troy C. Sarich, Kajs-Marie Schützer, Maria Wollbratt, Ulrika Wall, Eva Kessler, and Ulf G. Eriksson

No Pharmacokinetic or Pharmacodynamic Interaction Between Digoxin and the Oral Direct Thrombin Inhibitor Ximelagatran in Healthy Volunteers
J Clin Pharmacol 2004 44: 935. [Abstract] [Full Text] [PDF]  

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