Regulatory Science:

Shiew-Mei Huang and Lawrence J. Lesko

Drug-Drug, Drug-Dietary Supplement, and Drug-Citrus Fruit and Other Food Interactions: What Have We Learned?
J Clin Pharmacol 2004 44: 559. [Abstract] [Full Text] [PDF]  

Methods:

Joseph D. Ma, Anne N. Nafziger, Angela D. M. Kashuba, Myong-Jin Kim, Andrea Gaedigk, Elizabeth Rowland, Jooran S. Kim, and Joseph S. Bertino, Jr.

Limited Sampling Strategy of S-Warfarin Concentrations, but Not Warfarin S/R Ratios, Accurately Predicts S-Warfarin AUC during Baseline and Inhibition in CYP2C9 Extensive Metabolizers
J Clin Pharmacol 2004 44: 570. [Abstract] [Full Text] [PDF]  

Pharmacogenetics:

Lian-Sheng Wang, Bing Zhu, A. M. Abd El-Aty, Gan Zhou, Zhi Li, Jun Wu, Guo-Lin Chen, Jie Liu, Zhi Rong Tang, Wang An, Qing Li, Dan Wang, and Hong-Hao Zhou

The Influence of St. John's Wort on CYP2C19 Activity with Respect to Genotype
J Clin Pharmacol 2004 44: 577. [Abstract] [Full Text] [PDF]  

Ophelia Q. P. Yin, Brian Tomlinson, Albert H. L. Chow, Mary M. Y. Waye, and Moses S. S. Chow

Omeprazole as a CYP2C19 Marker in Chinese Subjects: Assessment of Its Gene-Dose Effect and Intrasubject Variability
J Clin Pharmacol 2004 44: 582. [Abstract] [Full Text] [PDF]  

Pharmacokinetics and Pharmacodynamics:

James A. Dowell, William Knebel, Tom Ludden, Marty Stogniew, David Krause, and Tim Henkel

Population Pharmacokinetic Analysis of Anidulafungin, an Echinocandin Antifungal
J Clin Pharmacol 2004 44: 590. [Abstract] [Full Text] [PDF]  

Lucy Lee, Mohammad Hossain, Yanfeng Wang, and Greg Sedek

Absorption of Rivastigmine from Different Regions of the Gastrointestinal Tract in Humans
J Clin Pharmacol 2004 44: 599. [Abstract] [Full Text] [PDF]  

David J. Greenblatt, Bruce L. Ehrenberg, Kerry E. Culm, Joseph M. Scavone, Kathleen E. Corbett, Hylar L. Friedman, Jerold S. Harmatz, and Richard I. Shader

Kinetics and EEG Effects of Midazolam during and after 1-Minute, 1-Hour, and 3-Hour Intravenous Infusions
J Clin Pharmacol 2004 44: 605. [Abstract] [Full Text] [PDF]  

Barry Dvorchik and David Damphousse

Single-Dose Pharmacokinetics of Daptomycin in Young and Geriatric Volunteers
J Clin Pharmacol 2004 44: 612. [Abstract] [Full Text] [PDF]  

Marc Pfister, Nancy E. Martin, Lloyd P. Haskell, and Jeffrey S. Barrett

Optimizing Dose Selection with Modeling and Simulation: Application to the Vasopeptidase Inhibitor M100240
J Clin Pharmacol 2004 44: 621. [Abstract] [Full Text] [PDF]  

Teaching Series:

Suzanne Shuk Ching Lee, Pui-Yin Pauline Cheung, and Moses Sing Sum Chow

Benefits of Individualized Counseling by the Pharmacist on the Treatment Outcomes of Hyperlipidemia in Hong Kong
J Clin Pharmacol 2004 44: 632. [Abstract] [Full Text] [PDF]  

Drug Interactions:

Jean Spénard, Christian Aumais, Julie Massicotte, Claude Tremblay, and Marc Lefebvre

Influence of Omeprazole on Bioavailability of Bismuth following Administration of a Triple Capsule of Bismuth Biskalcitrate, Metronidazole, and Tetracycline
J Clin Pharmacol 2004 44: 640. [Abstract] [Full Text] [PDF]  

Jyoti Kalbag, Cheryl Elder, Graham Scott, Yibin Wang, Slavica Milosavljev, Philipp Leese, Jacque Caldwell, and Christiane Rordorf

Concomitant Administration of Lumiracoxib and a Triphasic Oral Contraceptive Does Not Affect Contraceptive Activity or Pharmacokinetic Profile
J Clin Pharmacol 2004 44: 646. [Abstract] [Full Text] [PDF]  

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