Drug Metabolism:

Craig R. Shadle, Yih Lee, Anup K. Majumdar, Kevin J. Petty, Cynthia Gargano, Thomas E. Bradstreet, Judith K. Evans, and Robert A. Blum

Evaluation of Potential Inductive Effects of Aprepitant on Cytochrome P450 3A4 and 2C9 Activity
J Clin Pharmacol 2004 44: 215. [Abstract] [Full Text] [PDF]  

Evan D. Kharasch, Christine Hoffer, T. Gul Altuntas, and Dale Whittington

Quinidine as a Probe for the Role of P-Glycoprotein in the Intestinal Absorption and Clinical Effects of Fentanyl
J Clin Pharmacol 2004 44: 224. [Abstract] [Full Text] [PDF]  

Pharmacokinetics and Pharmacodynamics:

Jun Shi, Guy Montay, Sunny Chapel, Pierre Hardy, Jeffrey S. Barrett, Marshall Sack, Thomas Marbury, Suzanne K. Swan, Ramon Vargas, Violette Leclerc, Bruno Leroy, and Vijay O. Bhargava

Pharmacokinetics and Safety of the Ketolide Telithromycin in Patients with Renal Impairment
J Clin Pharmacol 2004 44: 234. [Abstract] [Full Text] [PDF]  

Noriko Daneshtalab, Richard Z. Lewanczuk, Anthony Russell, and Fakhreddin Jamali

Rheumatoid Arthritis Does Not Reduce the Pharmacodynamic Response to Valsartan
J Clin Pharmacol 2004 44: 245. [Abstract] [Full Text] [PDF]  

Lowell A. Borgen, Richard A. Okerholm, Allen Lai, and Martin B. Scharf

The Pharmacokinetics of Sodium Oxybate Oral Solution following Acute and Chronic Administration to Narcoleptic Patients
J Clin Pharmacol 2004 44: 253. [Abstract] [Full Text] [PDF]  

Stan S. Jhee, William H. Lyness, Patrick B. Rojas, Mark T. Leibowitz, Victoria Zarotsky, and Lisbeth V. Jacobsen

Similarity of Insulin Detemir Pharmacokinetics, Safety, and Tolerability Profiles in Healthy Caucasian and Japanese American Subjects
J Clin Pharmacol 2004 44: 258. [Abstract] [Full Text] [PDF]  

Chin-Chung Lin, Lee Philips, Christine Xu, and Li-Tain Yeh

Pharmacokinetics and Safety of Viramidine, a Prodrug of Ribavirin, in Healthy Volunteers
J Clin Pharmacol 2004 44: 265. [Abstract] [Full Text] [PDF]  

Carlos A. Rodríguez, Nkechi E. Azie, Gregory Adams, Kirsteen Donaldson, Steven F. Francom, Brian A. Staton, and Paul A. Bombardt

Single Oral Dose Safety, Tolerability, and Pharmacokinetics of PNU-96391 in Healthy Volunteers
J Clin Pharmacol 2004 44: 276. [Abstract] [Full Text] [PDF]  

Satoshi Sobue, Kaneo Sekiguchi, Katsuyoshi Shimatani, and Keith Tan

Pharmacokinetics and Safety of Fosf luconazole after Single Intravenous Bolus Injection in Healthy Male Japanese Volunteers
J Clin Pharmacol 2004 44: 284. [Abstract] [Full Text] [PDF]  

Drug Interactions:

Mark J. Shelton, Denise Cloen, Robin DiFrancesco, Charles S. Berenson, Andrew Esch, Pascal J. de Caprariis, Branka Palic, Jane L. Schur, Christopher J. L. Buggé, Anders Ljungqvist, Orlando Espinosa, and Ross G. Hewitt

The Effects of Once-Daily Saquinavir/Minidose Ritonavir on the Pharmacokinetics of Methadone
J Clin Pharmacol 2004 44: 293. [Abstract] [Full Text] [PDF]  

Walter K. Kraft, Jacqueline B. McCrea, Gregory A. Winchell, Alexandra Carides, Richard Lowry, Eric J. Woolf, Sandra E. Kusma, Paul J. Deutsch, Howard E. Greenberg, and Scott A. Waldman

Indinavir and Rifabutin Drug Interactions in Healthy Volunteers
J Clin Pharmacol 2004 44: 305. [Abstract] [Full Text] [PDF]  

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