Special Review:

Adam T. Harder and Yuehuei H. An

The Mechanisms of the Inhibitory Effects of Nonsteroidal Anti-Inflammatory Drugs on Bone Healing: A Concise Review
J Clin Pharmacol 2003 43: 807. [Abstract] [Full Text] [PDF]  

Pharmacogenetics:

Richard Judson

Using Multiple Drug Exposure Levels to Optimize Power in Pharmacogenetic Trials
J Clin Pharmacol 2003 43: 816. [Abstract] [Full Text] [PDF]  

Clinical Studies:

Haralampos J. Milionis, John Papakostas, Anna Kakafika, George Chasiotis, Konstantine Seferiadis, and Moses S. Elisaf

Comparative Effects of Atorvastatin, Simvastatin, and Fenofibrate on Serum Homocysteine Levels in Patients with Primary Hyperlipidemia
J Clin Pharmacol 2003 43: 825. [Abstract] [Full Text] [PDF]  

Drug Metabolism:

Maria L. Veronese, Lisa P. Gillen, Joanne P. Burke, Ellen P. Dorval, Walter W. Hauck, Ed Pequignot, Scott A. Waldman, and Howard E. Greenberg

Exposure-Dependent Inhibition of Intestinal and Hepatic CYP3A4 In Vivo by Grapefruit Juice
J Clin Pharmacol 2003 43: 831. [Abstract] [Full Text] [PDF]  

Pediatrics:

Gregory L. Kearns, Tommy Andersson, Laura P. James, Andrea Gaedigk, Rebecca A. Kraynak, Susan M. Abdel-Rahman, Krishnaswami Ramabadran, John N. van den Anker, and the Pediatric Pharmacology Research Unit Network

Omeprazole Disposition in Children following Single-Dose Administration
J Clin Pharmacol 2003 43: 840. [Abstract] [Full Text] [PDF]  

Analgesia:

G. A. Bjørnsson, H. R. Haanæs, and L. A. Skoglund

Naproxen 500 mg bid versus Acetaminophen 1000 mg qid: Effect on Swelling and Other Acute Postoperative Events after Bilateral Third Molar Surgery
J Clin Pharmacol 2003 43: 849. [Abstract] [Full Text] [PDF]  

Pharmacokinetics and Pharmacodynamics:

Hitoshi Tada, Sigeru Satoh, Masahiro Iinuma, Naotake Shimoda, Miho Murakami, Yukitoshi Hayase, Tetsuro Kato, and Toshio Suzuki

Chronopharmacokinetics of Tacrolimus in Kidney Transplant Recipients: Occurrence of Acute Rejection
J Clin Pharmacol 2003 43: 859. [Abstract] [Full Text] [PDF]  

D. R. J. Kuypers, K. Claes, P. Evenepoel, B. Maes, W. Coosemans, J. Pirenne, and Y. Vanrenterghem

Long-Term Changes in Mycophenolic Acid Exposure in Combination with Tacrolimus and Corticosteroids Are Dose Dependent and Not Reflected by Trough Plasma Concentration: A Prospective Study in 100 De Novo Renal Allograft Recipients
J Clin Pharmacol 2003 43: 866. [Abstract] [Full Text] [PDF]  

Kou-Yi Tserng, Stephen T. Ingalls, Erik M. Boczko, Timothy P. Spiro, Xiaolin Li, Susan Majka, Stanton L. Gerson, James K. V. Willson, and Charles L. Hoppel

Pharmacokinetics of O⁶-Benzylguanine (NSC637037) and Its Metabolite, 8-Oxo-O⁶-Benzylguanine
J Clin Pharmacol 2003 43: 881. [Abstract] [Full Text] [PDF]  

Josephia R. Muindi, John W. Wilson, Ying Peng, Mary Jo Capozolli, Candace S. Johnson, and Donald L. Trump

A Limited Sampling Method for the Estimation of Serum Calcitriol Area under the Curve in Cancer Patients
J Clin Pharmacol 2003 43: 894. [Abstract] [Full Text] [PDF]  

Antoine Tarral, Philippe Dostert, Yann Guillevic, Laura Fabbri, Ivano Rondelli, Fabrizia Mariotti, and Bruno P. Imbimbo

Safety, Pharmacokinetics, and Pharmacodynamics of CHF 3381, a Novel N-Methyl-D-Aspartate Antagonist, after Single Oral Doses in Healthy Subjects
J Clin Pharmacol 2003 43: 901. [Abstract] [Full Text] [PDF]  

Drug Interactions:

Martin Feuring, Yih Lee, Laura H. Orlowski, Nicole Michiels, Marina De Smet, Anup K. Majumdar, Kevin J. Petty, Michael R. Goldberg, M. Gail Murphy, Keith M. Gottesdiener, Michael Hesney, L. Ellen Brackett, and Martin Wehling

Lack of Effect of Aprepitant on Digoxin Pharmacokinetics in Healthy Subjects
J Clin Pharmacol 2003 43: 912. [Abstract] [Full Text] [PDF]  

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