Editorials:

Deborah L. Keefe

Wayne A. Colburn
J Clin Pharmacol 2003 43: 327. [Full Text] [PDF]  

Drug Development:

Wayne A. Colburn

Biomarkers in Drug Discovery and Development: From Target Identification through Drug Marketing
J Clin Pharmacol 2003 43: 329. [Abstract] [Full Text] [PDF]  

Lawrence J. Lesko, Ronald A. Salerno, Brian B. Spear, Donald C. Anderson, Timothy Anderson, Celia Brazell, Jerry Collins, Andrew Dorner, David Essayan, Baltazar Gomez-Mancilla, Joseph Hackett, Shiew-Mei Huang, Susan Ide, Joanne Killinger, John Leighton, Elizabeth Mansfield, Robert Meyer, Stephen G. Ryan, Virginia Schmith, Peter Shaw, Frank Sistare, Mark Watson, and Alexandra Worobec

Pharmacogenetics and Pharmacogenomics in Drug Development and Regulatory Decision Making: Report of the First FDA-PWG-PhRMA-DruSafe Workshop
J Clin Pharmacol 2003 43: 342. [Abstract] [Full Text] [PDF]  

Pharmacokinetics and Pharmacodynamics:

Suzanne K. Swan, Honghui Zhou, Ann Horowitz, Latifa Alladina, Martine Hubert, Silke Appel-Dingemanse, Stuart Osborne, Larry Lambrecht, and James F. McLeod

Tegaserod Pharmacokinetics Are Similar in Patients with Severe Renal Insufficiency and in Healthy Subjects
J Clin Pharmacol 2003 43: 359. [Abstract] [Full Text] [PDF]  

S. Rohatagi, V. Arya, K. Zech, R. Nave, G. Hochhaus, B. K. Jensen, and J. S. Barrett

Population Pharmacokinetics and Pharmacodynamics of Ciclesonide
J Clin Pharmacol 2003 43: 365. [Abstract] [Full Text] [PDF]  

K. C. Hayes, M. A. Katz, J. G. Devane, J. T. C. Hsieh, D. L. Wolfe, P. J. Potter, and A. R. Blight

Pharmacokinetics of an Immediate-Release Oral Formulation of Fampridine (4-Aminopyridine) in Normal Subjects and Patients with Spinal Cord Injury
J Clin Pharmacol 2003 43: 379. [Abstract] [Full Text] [PDF]  

Tsiri Agbenyega, Tim Planche, George Bedu-Addo, Daniel Ansong, Alex Owusu-Ofori, Venkatesh A. Bhattaram, Nelamangala V. Nagaraja, Albert L. Shroads, George N. Henderson, Alan D. Hutson, Hartmut Derendorf, Sanjeev Krishna, and Peter W. Stacpoole

Population Kinetics, Efficacy, and Safety of Dichloroacetate for Lactic Acidosis Due to Severe Malaria in Children
J Clin Pharmacol 2003 43: 386. [Abstract] [Full Text] [PDF]  

Francisco Abad-Santos, M^a Angeles Gálvez-Múgica, M^a Angeles Santos, Jesús Novalbos, Sonia Gallego-Sandín, Paloma Méndez, Cesar Casimiro, and Fernando Gilsanz

Pharmacokinetics and Pharmacodynamics of a Single Bolus of Propofol 2% in Healthy Volunteers
J Clin Pharmacol 2003 43: 397. [Abstract] [Full Text] [PDF]  

Dolly A. Parasrampuria, Peter de Boer, Daksha Desai-Krieger, Andrew T. Chow, and C. Richard Jones

Single-Dose Pharmacokinetics and Pharmacodynamics of RWJ 67657, a Specific p38 Mitogen-Activated Protein Kinase Inhibitor: A First-in-Human Study
J Clin Pharmacol 2003 43: 406. [Abstract] [Full Text] [PDF]  

Drug Interactions:

David J. Greenblatt, Lisa L. von Moltke, Jerold S. Harmatz, Steven M. Fogelman, Gengsheng Chen, Jennifer A. Graf, Polyxane Mertzanis, Susan Byron, Kerry E. Culm, Brian W. Granda, Johanna P. Daily, and Richard I. Shader

Short-Term Exposure to Low-Dose Ritonavir Impairs Clearance and Enhances Adverse Effects of Trazodone
J Clin Pharmacol 2003 43: 414. [Abstract] [Full Text] [PDF]  

Joseph C. Fleishaker, Beth D. Herman, Barbara J. Carel, and Nkechi E. Azie

Interaction between Ketoconazole and Almotriptan in Healthy Volunteers
J Clin Pharmacol 2003 43: 423. [Abstract] [Full Text] [PDF]  

Jianguo Zhi, Rema Moore, Linda Kanitra, and Thomas E. Mulligan

Effects of Orlistat, a Lipase Inhibitor, on the Pharmacokinetics of Three Highly Lipophilic Drugs (Amiodarone, Fluoxetine, and Simvastatin) in Healthy Volunteers
J Clin Pharmacol 2003 43: 428. [Abstract] [Full Text] [PDF]  

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