Therapeutic Review:

Arnold R. Gammaitoni, Nancy A. Alvarez, and Bradley S. Galer

Safety and Tolerability of the Lidocaine Patch 5%, a Targeted Peripheral Analgesic: A Review of the Literature
J Clin Pharmacol 2003 43: 111. [Abstract] [Full Text] [PDF]  

Drug Development:

Ralph Stern, Francoise Chanoine, and Kay Criswell

Are Coagulation Times Biomarkers? Data from a Phase I Study of the Oral Thrombin Inhibitor LB-30057 (CI-1028)
J Clin Pharmacol 2003 43: 118. [Abstract] [Full Text] [PDF]  

Drug Metabolism:

Norio Yasui-Furukori, Kazuo Mihara, Tsuyoshi Kondo, Takahiro Kubota, Tatsuji Iga, Yutaka Takarada, Ronald De Vries, Sunao Kaneko, and Tomonori Tateishi

Effects of CYP2D6 Genotypes on Plasma Concentrations of Risperidone and Enantiomers of 9-Hydroxyrisperidone in Japanese Patients with Schizophrenia
J Clin Pharmacol 2003 43: 122. [Abstract] [Full Text] [PDF]  

Pediatrics:

Jeffrey L. Blumer, Stephen R. Daniels, William J. Dreyer, Donald Batisky, Philip D. Walson, Doina Roman, and Daniele Ouellet

Pharmacokinetics of Quinapril in Children: Assessment during Substitution for Chronic Angiotensin-Converting Enzyme Inhibitor Treatment
J Clin Pharmacol 2003 43: 128. [Abstract] [Full Text] [PDF]  

Edmund V. Capparelli, Janet A. Englund, James D. Connor, Stephen A. Spector, Ross E. McKinney, Paul Palumbo, Carol J. Baker, and the PACTG 152 Team

Population Pharmacokinetics and Pharmacodynamics of Zidovudine in HIV-Infected Infants and Children
J Clin Pharmacol 2003 43: 133. [Abstract] [Full Text] [PDF]  

John M. Kovarik, Adele Noe, Stephane Berthier, Louis McMahon, Wayne K. Langholff, Alan S. Marion, Peter Friedrich Hoyer, Robert Ettenger, and Christiane Rordorf

Clinical Development of an Everolimus Pediatric Formulation: Relative Bioavailability, Food Effect, and Steady-State Pharmacokinetics
J Clin Pharmacol 2003 43: 141. [Abstract] [Full Text] [PDF]  

Pharmacokinetics and Pharmacodynamics:

Susan M. Abdel-Rahman, Franklin K. Johnson, Ginette Gauthier-Dubois, Irving E. Weston, and Gregory L. Kearns

The Bioequivalence of Nizatidine (Axid®) in Two Extemporaneously and One Commercially Prepared Oral Liquid Formulations Compared with Capsule
J Clin Pharmacol 2003 43: 148. [Abstract] [Full Text] [PDF]  

Andrej Skerjanec, James Berenson, ChyiHung Hsu, Pierre Major, Wilson H. Miller, Jr., Christina Ravera, Horst Schran, John Seaman, and Felix Waldmeier

The Pharmacokinetics and Pharmacodynamics of Zoledronic Acid in Cancer Patients with Varying Degrees of Renal Function
J Clin Pharmacol 2003 43: 154. [Abstract] [Full Text] [PDF]  

Damayanthi Devineni, Yulia H. Walter, Harold T. Smith, James S. Lee, Pratapa Prasad, and James F. McLeod

Pharmacokinetics of Nateglinide in Renally Impaired Diabetic Patients
J Clin Pharmacol 2003 43: 163. [Abstract] [Full Text] [PDF]  

Mark J. Shelton, Ross G. Hewitt, John M. Adams, Steve R. Cox, James H. Chambers, and Gene D. Morse

Delavirdine Malabsorption in HIV-Infected Subjects with Spontaneous Gastric Hypoacidity
J Clin Pharmacol 2003 43: 171. [Abstract] [Full Text] [PDF]  

Drug Interactions:

Qinying Zhao, Charles Xie, Luana Pesco-Koplowitz, Xinwei Jia, and Jean-Loup Parier

Pharmacokinetic and Safety Assessments of Concurrent Administration of Risperidone and Donepezil
J Clin Pharmacol 2003 43: 180. [Abstract] [Full Text] [PDF]  

Jules I. Schwartz, Saurabh Mukhopadhyay, Arturo G. Porras, Kala-Jyoti Viswanathan-Aiyer, Sherilyn Adcock, David L. Ebel, and Barry J. Gertz

Effect of Rofecoxib on Prednisolone and Prednisone Pharmacokinetics in Healthy Subjects
J Clin Pharmacol 2003 43: 187. [Abstract] [Full Text] [PDF]  

Adverse Events:

Pramod Kumar Sharma, Samir Malhotra, Promila Pandhi, and Narinder Kumar

Effect of Inhaled Steroids on Bone Mineral Density: A Meta-Analysis
J Clin Pharmacol 2003 43: 193. [Abstract] [Full Text] [PDF]  

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