Articles:

LJ Lesko, M Rowland, CC Peck, and TF Blaschke

Optimizing the science of drug development: opportunities for better candidate selection and accelerated evaluation in humans
J Clin Pharmacol 2000 40: 803. [Abstract] [PDF]  

GL Bakris, P Whelton, M Weir, A Mimran, W Keane, and E Schiffrin

The future of clinical trials in chronic renal disease: outcome of an NIH/FDA/Physician Specialist Conference. Evaluation of Clinical Trial Endpoints in Chronic Renal Disease Study Group
J Clin Pharmacol 2000 40: 815. [Abstract] [PDF]  

A Yacobi, E Masson, D Moros, D Ganes, C Lapointe, Z Abolfathi, M LeBel, Y Golander, D Doepner, T Blumberg, Y Cohen, and B Levitt

Who needs individual bioequivalence studies for narrow therapeutic index drugs? A case for warfarin
J Clin Pharmacol 2000 40: 826. [Abstract] [PDF]  

JW Massarella, GZ He, A Dorr, K Nieforth, P Ward, and A Brown

The pharmacokinetics and tolerability of the oral neuraminidase inhibitor oseltamivir (Ro 64-0796/GS4104) in healthy adult and elderly volunteers
J Clin Pharmacol 2000 40: 836. [Abstract] [PDF]  

D Tenero, S Boike, D Boyle, B Ilson, HF Fesniak, S Brozena, and D Jorkasky

Steady-state pharmacokinetics of carvedilol and its enantiomers in patients with congestive heart failure
J Clin Pharmacol 2000 40: 844. [Abstract] [PDF]  

R Durso, JE Evans, E Josephs, G Szabo, B Evans, HH Fernandez, and TR Browne

Variable absorption of carbidopa affects both peripheral and central levodopa metabolism
J Clin Pharmacol 2000 40: 854. [Abstract] [PDF]  

JQ Dong, L Ni, CS Scott, GZ Retsch-Bogart, and PC Smith

Pharmacokinetics of ibuprofen enantiomers in children with cystic fibrosis
J Clin Pharmacol 2000 40: 861. [Abstract] [PDF]  

AR Gascon, E Campo, RM Hernandez, B Calvo, J Errasti, and JL Pedraz Munoz

Pharmacokinetics of ofloxacin enantiomers after intravenous administration for antibiotic prophylaxis in biliary surgery
J Clin Pharmacol 2000 40: 869. [Abstract] [PDF]  

MR Marino, NN Vachharajani, and OW Hadjilambris

Irbesartan does not affect the pharmacokinetics of simvastatin in healthy subjects
J Clin Pharmacol 2000 40: 875. [Abstract] [PDF]  

KH Dykstra, H Rogge, A Stone, J Loewy, Keith JC, Jr, and US Schwertschlag

Mechanism and amelioration of recombinant human interleukin-11 (rhIL-11)-induced anemia in healthy subjects
J Clin Pharmacol 2000 40: 880. [Abstract] [PDF]  

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