Articles:

DL Keefe

Clinical pharmacology of telmisartan:
J Clin Pharmacol 2000 40: 1311. [PDF]  

J Stangier, J Schmid, D Turck, H Switek, A Verhagen, PA Peeters, SP van Marle, WJ Tamminga, FA Sollie, and JH Jonkman

Absorption, metabolism, and excretion of intravenously and orally administered [14C]telmisartan in healthy volunteers
J Clin Pharmacol 2000 40: 1312. [Abstract] [PDF]  

CL Young, VC Dias, and J Stangier

Multiple-dose pharmacokinetics of telmisartan and of hydrochlorothiazide following concurrent administration in healthy subjects
J Clin Pharmacol 2000 40: 1323. [Abstract] [PDF]  

J Stangier, CA Su, MG Hendriks, JJ van Lier, FA Sollie, B Oosterhuis, and JH Jonkman

Steady-state pharmacodynamics and pharmacokinetics of warfarin in the presence and absence of telmisartan in healthy male volunteers
J Clin Pharmacol 2000 40: 1331. [Abstract] [PDF]  

J Stangier, CA Su, A Fraunhofer, and W Tetzloff

Pharmacokinetics of acetaminophen and ibuprofen when coadministered with telmisartan in healthy volunteers
J Clin Pharmacol 2000 40: 1338. [Abstract] [PDF]  

J Stangier and CA Su

Pharmacokinetics of repeated oral doses of amlodipine and amlodipine plus telmisartan in healthy volunteers
J Clin Pharmacol 2000 40: 1347. [Abstract] [PDF]  

J Stangier, CA Su, G Schondorfer, and W Roth

Pharmacokinetics and safety of intravenous and oral telmisartan 20 mg and 120 mg in subjects with hepatic impairment compared with healthy volunteers
J Clin Pharmacol 2000 40: 1355. [Abstract] [PDF]  

J Stangier, CA Su, R Brickl, and H Franke

Pharmacokinetics of single-dose telmisartan 120 mg given during and between hemodialysis in subjects with severe renal insufficiency: comparison with healthy volunteers
J Clin Pharmacol 2000 40: 1365. [Abstract] [PDF]  

J Stangier, CA Su, MG Hendriks, JJ van Lier, FA Sollie, B Oosterhuis, and JH Jonkman

The effect of telmisartan on the steady-state pharmacokinetics of digoxin in healthy male volunteers
J Clin Pharmacol 2000 40: 1373. [Abstract] [PDF]  

DH Smith, KM Matzek, and J Kempthorne-Rawson

Dose response and safety of telmisartan in patients with mild to moderate hypertension
J Clin Pharmacol 2000 40: 1380. [Abstract] [PDF]  

H Derendorf, LJ Lesko, P Chaikin, WA Colburn, P Lee, R Miller, R Powell, G Rhodes, D Stanski, and J Venitz

Pharmacokinetic/pharmacodynamic modeling in drug research and development
J Clin Pharmacol 2000 40: 1399. [Abstract] [PDF]  

WA Colburn

Optimizing the use of biomarkers, surrogate endpoints, and clinical endpoints for more efficient drug development
J Clin Pharmacol 2000 40: 1419. [Abstract] [PDF]  

P Chaikin, GR Rhodes, R Bruno, S Rohatagi, and C Natarajan

Pharmacokinetics/pharmacodynamics in drug development: an industrial perspective
J Clin Pharmacol 2000 40: 1428. [Abstract] [PDF]  

I Mahmood

Interspecies scaling: role of protein binding in the prediction of clearance from animals to humans
J Clin Pharmacol 2000 40: 1439. [Abstract] [PDF]  

S Naude, S Clijsen, G Naulaers, H Daniels, C Vanhole, and H Devlieger

Iron supplementation in preterm infants: a study comparing the effect and tolerance of a Fe2+ and a nonionic FeIII compound
J Clin Pharmacol 2000 40: 1447. [Abstract] [PDF]  

CD Stowe, KR Lee, SA Storgion, and SJ Phelps

Altered phenytoin pharmacokinetics in children with severe, acute traumatic brain injury
J Clin Pharmacol 2000 40: 1452. [Abstract] [PDF]  

JA Sandberg, VP Parker, KS Blanchard, D Sweedler, JA Powell, A Kachensky, L Bellon, N Usman, T Rossing, E Borden, and LM Blatt

Pharmacokinetics and tolerability of an antiangiogenic ribozyme (ANGIOZYME) in healthy volunteers
J Clin Pharmacol 2000 40: 1462. [Abstract] [PDF]  

JV St Peter, LJ Lambrecht, BW Gunderson, SA Andersen, SC Gallagher, and SK Swan

Pharmacokinetics of pilocarpine in subjects with varying degrees of renal function
J Clin Pharmacol 2000 40: 1470. [Abstract] [PDF]  

F Kersting, A Selenka, and S Walch

Effects of cholestyramine on vitamin E levels in patients treated with statins
J Clin Pharmacol 2000 40: 1476. [Abstract] [PDF]  

BN Nguyen, RB Parker, M Noujedehi, JM Sullivan, and JA Johnson

Effects of COER-verapamil on circadian pattern of forearm vascular resistance and blood pressure
J Clin Pharmacol 2000 40: 1480. [Abstract] [PDF]  

D Herrera, L Mayet, MC Galindo, and H Jung

Pharmacokinetics of a sustained-release dosage form of clomipramine
J Clin Pharmacol 2000 40: 1488. [Abstract] [PDF]  

PH Marathe, ME Arnold, J Meeker, DS Greene, and RH Barbhaiya

Pharmacokinetics and bioavailability of a metformin/glyburide tablet administered alone and with food
J Clin Pharmacol 2000 40: 1494. [Abstract] [PDF]  

TJ Cleophas

Crossover trials should not be used to test one treatment against another treatment with a totally different chemical class/mode of action
J Clin Pharmacol 2000 40: 1503. [Abstract] [PDF]  

HE Greenberg, K Gottesdiener, M Huntington, P Wong, P Larson, L Wildonger, L Gillen, E Dorval, and SA Waldman

A new cyclooxygenase-2 inhibitor, rofecoxib (VIOXX), did not alter the antiplatelet effects of low-dose aspirin in healthy volunteers
J Clin Pharmacol 2000 40: 1509. [Abstract] [PDF]  

RA Di Cicco, AK Miller, S Patterson, and MI Freed

Rosiglitazone does not affect the steady-state pharmacokinetics of digoxin
J Clin Pharmacol 2000 40: 1516. [Abstract] [PDF]  

GW Amsden, AN Nafziger, G Foulds, and LJ Cabelus

A study of the pharmacokinetics of azithromycin and nelfinavir when coadministered in healthy volunteers
J Clin Pharmacol 2000 40: 1522. [Abstract] [PDF]  

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