Editorials:

JC Somberg

New FDA initiatives
J Clin Pharmacol 1993 33: 587. [PDF]  

Articles:

R Kozlik-Feldmann, HH Kramer, H Wicht, R Feldmann, H Netz, and D Reinhardt

Distribution of myocardial beta-adrenoceptor subtypes and coupling to the adenylate cyclase in children with congenital heart disease and implications for treatment
J Clin Pharmacol 1993 33: 588. [Abstract] [PDF]  

R Lieberman

FK506, artificial intelligence and pharmacoeconomics
J Clin Pharmacol 1993 33: 596. [PDF]  

J McMichael, R Lieberman, H Doyle, J McCauley, J Fung, and TE Starzl

An intelligent and cost-effective computer dosing system for individualizing FK506 therapy in transplantation and autoimmune disorders
J Clin Pharmacol 1993 33: 599. [Abstract] [PDF]  

AB Jain, K Abu-Elmagd, H Abdallah, V Warty, J Fung, S Todo, TE Starzl, and R Venkataramanan

Pharmacokinetics of FK506 in liver transplant recipients after continuous intravenous infusion
J Clin Pharmacol 1993 33: 606. [Abstract] [PDF]  

WH Frishman

A new extended-release formulation of diltiazem HCl for the treatment of mild-to-moderate hypertension
J Clin Pharmacol 1993 33: 612. [Abstract] [PDF]  

JE Tisdale, J Kluger, Fisher, JR, and MS Chow

Efficacy of class 1C antiarrhythmic agents in patients with inducible ventricular tachycardia refractory to therapy with class 1A antiarrhythmic drugs
J Clin Pharmacol 1993 33: 623. [Abstract] [PDF]  

LK Tay, MA Sciacca, MB Sostrin, RH Farmen, and KA Pittman

Effect of food on the bioavailability of gepirone in humans
J Clin Pharmacol 1993 33: 631. [Abstract] [PDF]  

OL Laskin, PM Patterson, S Shingo, KC Lasseter, and EC Shamblen

Pharmacodynamics and dose-response relationship of famotidine: a double-blind randomized placebo-controlled trial
J Clin Pharmacol 1993 33: 636. [Abstract] [PDF]  

T Sudoh, A Fujimura, T Shiga, T Tateishi, K Sunaga, K Ohashi, and A Ebihara

Influence of lisinopril on urinary electrolytes excretion after furosemide in healthy subjects
J Clin Pharmacol 1993 33: 640. [Abstract] [PDF]  

RD Prather, TG Tu, CN Rolf, and J Gorsline

Nicotine pharmacokinetics of Nicoderm (nicotine transdermal system) in women and obese men compared with normal-sized men
J Clin Pharmacol 1993 33: 644. [Abstract] [PDF]  

DJ Greenblatt

Presystemic extraction: mechanisms and consequences
J Clin Pharmacol 1993 33: 650. [Abstract] [PDF]  

D Lalka, RK Griffith, and CL Cronenberger

The hepatic first-pass metabolism of problematic drugs
J Clin Pharmacol 1993 33: 657. [Abstract] [PDF]  

J Somberg, G Shroff, S Khosla, and S Ehrenpreis

The clinical implications of first-pass metabolism: treatment strategies for the 1990s
J Clin Pharmacol 1993 33: 670. [Abstract] [PDF]  

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