Articles:

R Mechoulam

Current status of therapeutic opportunities based on cannabinoid research. An overview
J Clin Pharmacol 1981 21: S2 -S7. [PDF]  

JS Penta, DS Poster, S Bruno, and JS Macdonald

Clinical trials with antiemetic agents in cancer patients receiving chemotherapy
J Clin Pharmacol 1981 21: S11 -S22. [Abstract] [PDF]  

HL Borison, R Borison, and LE McCarthy

Phylogenic and neurologic aspects of the vomiting process
J Clin Pharmacol 1981 21: S23 -S29. [Abstract] [PDF]  

LE McCarthy and HL Borison

Antiemetic activity of N-methyllevonantradol and nabilone in cisplatin-treated cats
J Clin Pharmacol 1981 21: S30 -S37. [Abstract] [PDF]  

JA Neidhart, MM Gagen, HE Wilson, and DC Young

Comparative trial of the antiemetic effects of THC and haloperidol
J Clin Pharmacol 1981 21: S38 -S42. [Abstract] [PDF]  

CM Cronin, SE Sallan, R Gelber, VS Lucas, and J Laszlo

Antiemetic effect of intramuscular levonantradol in patients receiving anticancer chemotherapy
J Clin Pharmacol 1981 21: S43 -S50. [Abstract] [PDF]  

J Laszlo, Lucas VS, Jr, DC Hanson, CM Cronin, and SE Sallan

Levonantradol for chemotherapy-induced emesis: phase I-II oral administration
J Clin Pharmacol 1981 21: S51 -S56. [Abstract] [PDF]  

S Garb

Cannabinoids in the management of severe nausea and vomiting from cancer chemotherapy. Some additional considerations
J Clin Pharmacol 1981 21: S57 -S59. [Abstract] [PDF]  

M Staquet, D Bron, M Rozencweig, and Y Kenis

Clinical studies with a THC analog (BRL-4664) in the prevention of cisplatin-induced vomiting
J Clin Pharmacol 1981 21: S60 -S63. [Abstract] [PDF]  

LH Einhorn, C Nagy, B Furnas, and SD Williams

Nabilone: an effective antiemetic in patients receiving cancer chemotherapy
J Clin Pharmacol 1981 21: S64 -S69. [Abstract] [PDF]  

DL Sweet, NJ Miller, W Weddington, E Senay, and L Sushelsky

delta 9-Tetrahydrocannabinol as an antiemetic for patients receiving cancer chemotherapy. A pilot study
J Clin Pharmacol 1981 21: S70 -S75. [Abstract] [PDF]  

LE Orr and JF McKernan

Antiemetic effect of delta 9-tetrahydrocannabinol in chemotherapy-associated nausea and emesis as compared to placebo and compazine
J Clin Pharmacol 1981 21: S76 -S80. [Abstract] [PDF]  

RB Diasio, DS Ettinger, and BE Satterwhite

Oral levonantradol in the treatment of chemotherapy-induced emesis: preliminary observations
J Clin Pharmacol 1981 21: S81 -S85. [Abstract] [PDF]  

ME Heim, W Romer, and W Queisser

Clinical experience with levonantradol hydrochloride in the prevention of cancer chemotherapy-induced nausea and vomiting
J Clin Pharmacol 1981 21: S86 -S89. [Abstract] [PDF]  

Riggs CE, Jr, MJ Egorin, JZ Fuks, N Schnaper, P Duffey, OM Colvin, J Aisner, PH Wiernik, and NR Bachur

Initial observations on the effects of delta 9-tetrahydrocannabinol on the plasma pharmacokinetics of cyclophosphamide and doxorubicin
J Clin Pharmacol 1981 21: S90 -S98. [Abstract] [PDF]  

Wolff JS, 3rd, GR Hemsworth, M DeMaio, and D Sloan

The effects of levonantradol hydrochloride on tumor growth and therapy
J Clin Pharmacol 1981 21: S99 -S102. [Abstract] [PDF]  

M Levitt, A Wilson, D Bowman, S Kemel, G Krepart, V Marks, H Schipper, G Thomson, B Weinerman, and R Weinerman

Physiologic observations in a controlled clinical trial of the antiemetic effectiveness of 5, 10, and 15 mg of delta 9-tetrahydrocannabinol in cancer chemotherapy. Ophthalmologic implications
J Clin Pharmacol 1981 21: S103 -S109. [Abstract] [PDF]  

JA Scigliano

THC therapeutic research by independent and state-sponsored investigators: a historical review
J Clin Pharmacol 1981 21: S113 -S121. [Abstract] [PDF]  

D Abraham, KR Pina, and JP Davignon

Mechanism for national distribution of delta 9-tetrahydrocannabinol (NSC-134454)
J Clin Pharmacol 1981 21: S122 -S127. [Abstract] [PDF]  

GJ Dow and FH Meyers

The California program for the investigational use of THC and marihuana in heterogeneous populations experiencing nausea and vomiting from anticancer therapy
J Clin Pharmacol 1981 21: S128 -S132. [Abstract] [PDF]  

RA Roffman

The Controlled Substances Therapeutic Research Act in the state of Washington
J Clin Pharmacol 1981 21: S133 -S140. [Abstract] [PDF]  

RT Jones, NL Benowitz, and RI Herning

Clinical relevance of cannabis tolerance and dependence
J Clin Pharmacol 1981 21: S143 -S152. [Abstract] [PDF]  

JT Ungerleider and T Andrysiak

Bias and the cannabis researcher
J Clin Pharmacol 1981 21: S153 -S158. [Abstract] [PDF]  

A Weissman

On the definition of cannabinoids: botanical? chemical? pharmacological?
J Clin Pharmacol 1981 21: S159 -S165. [Abstract] [PDF]  

FS van Dam, R Somers, and AL van Beek-Couzijn

Quality of life: some theoretical issues
J Clin Pharmacol 1981 21: S166 -S168. [Abstract] [PDF]  

LE Hollister, HK Gillespie, A Ohlsson, JE Lindgren, A Wahlen, and S Agurell

Do plasma concentrations of delta 9-tetrahydrocannabinol reflect the degree of intoxication?
J Clin Pharmacol 1981 21: S171 -S177. [Abstract] [PDF]  

ME Wall and M Perez-Reyes

The metabolism of delta 9-tetrahydrocannabinol and related cannabinoids in man
J Clin Pharmacol 1981 21: S178 -S189. [Abstract] [PDF]  

RM Shepard

Pharmacokinetics of levonantradol in laboratory animals and man
J Clin Pharmacol 1981 21: S190 -S200. [Abstract] [PDF]  

M Perez-Reyes, SM Owens, and S Di Guiseppi

The clinical pharmacology and dynamics of marihuana cigarette smoking
J Clin Pharmacol 1981 21: S201 -S207. [Abstract] [PDF]  

G Nahas, C Leger, B Tocque, and H Hoellinger

The kinetics of cannabinoid distribution and storage with special reference to the brain and testis
J Clin Pharmacol 1981 21: S208 -S214. [Abstract] [PDF]  

NL Benowitz and RT Jones

Cardiovascular and metabolic considerations in prolonged cannabinoid administration in man
J Clin Pharmacol 1981 21: S214 -S223. [Abstract] [PDF]  

RG Browne and A Weissman

Discriminative stimulus properties of delta 9-tetrahydrocannabinol: mechanistic studies
J Clin Pharmacol 1981 21: S227 -S234. [Abstract] [PDF]  

MA Geyer

Effects of levonantradol on habituation of startle in rats
J Clin Pharmacol 1981 21: S235 -S239. [Abstract] [PDF]  

S Burstein and SA Hunter

Prostaglandins and cannabis--VIII. Elevation of phospholipase A2 activity by cannabinoids in whole cells and subcellular preparations
J Clin Pharmacol 1981 21: S240 -S248. [Abstract] [PDF]  

EF Domino

Cannabinoids and the cholinergic system
J Clin Pharmacol 1981 21: S249 -S255. [Abstract] [PDF]  

E Costa, DL Cheney, and TF Murray

Levonantradol-induced inhibition of acetylcholine turnover in rat hippocampus and striatum
J Clin Pharmacol 1981 21: S256 -S261. [Abstract] [PDF]  

JP Leader, BK Koe, and A Weissman

GABA-like actions of levonantradol
J Clin Pharmacol 1981 21: S262 -S270. [Abstract] [PDF]  

MR Johnson, LS Melvin, TH Althuis, JS Bindra, CA Harbert, GM Milne, and A Weissman

Selective and potent analgetics derived from cannabinoids
J Clin Pharmacol 1981 21: S271 -S282. [Abstract] [PDF]  

CE Turner and MA Elsohly

Biological activity of cannabichromene, its homologs and isomers
J Clin Pharmacol 1981 21: S283 -S291. [Abstract] [PDF]  

Stambaugh JE, Jr

Pharmacokinetics and mechanisms of action of analgesics in clinical pain
J Clin Pharmacol 1981 21: S295 -S298. [Abstract] [PDF]  

WC Clark, MN Janal, P Zeidenberg, and GG Nahas

Effects of moderate and high doses of marihuana on thermal pain: a sensory decision theory analysis
J Clin Pharmacol 1981 21: S299 -S310. [Abstract] [PDF]  

PE Gilbert

A comparison of THC, nantradol, nabilone, and morphine in the chronic spinal dog
J Clin Pharmacol 1981 21: S311 -S319. [Abstract] [PDF]  

AK Jain, Ryan, JR, FG McMahon, and G Smith

Evaluation of intramuscular levonantradol and placebo in acute postoperative pain
J Clin Pharmacol 1981 21: S320 -S326. [Abstract] [PDF]  

JJ Jacob, K Ramabadran, and M Campos-Medeiros

A pharmacological analysis of levonantradol antinociception in mice
J Clin Pharmacol 1981 21: S327 -S333. [Abstract] [PDF]  

TL Yaksh

The antinociceptive effects of intrathecally administered levonantradol and desacetyllevonantradol in the rat
J Clin Pharmacol 1981 21: S334 -S340. [Abstract] [PDF]  

LA Dykstra

Effects of morphine, levonantradol, and N-methyllevonantradol on shock intensity discrimination
J Clin Pharmacol 1981 21: S341 -S347. [Abstract] [PDF]  

AM Young, JL Katz, and JH Woods

Behavioral effects of levonantradol and nantradol in the rhesus monkey
J Clin Pharmacol 1981 21: S348 -S360. [Abstract] [PDF]  

H Lal, DA Bennett, GT Shearman, MD McCarten, R Murphy, and A Angeja

Effectiveness of nantradol in blocking narcotic withdrawal signs through nonnarcotic mechanisms
J Clin Pharmacol 1981 21: S361 -S366. [Abstract] [PDF]  

Milne GM, Jr and MR Johnson

Levonantradol: a role for central prostanoid mechanisms?
J Clin Pharmacol 1981 21: S367 -S374. [Abstract] [PDF]  

LF Fabre and D McLendon

The efficacy and safety of nabilone (a synthetic cannabinoid) in the treatment of anxiety
J Clin Pharmacol 1981 21: S377 -S382. [Abstract] [PDF]  

RM Glass, EH Uhlenhuth, FW Hartel, CR Schuster, and MW Fischman

Single-dose study of nabilone in anxious volunteers
J Clin Pharmacol 1981 21: S383 -S396. [Abstract] [PDF]  

BK Koe and A Weissman

Facilitation of benzodiazepine binding by levonantradol
J Clin Pharmacol 1981 21: S397 -S405. [Abstract] [PDF]  

CL Ehlers, SJ Henriksen, and FE Bloom

Levonantradol potentiates the anticonvulsant effects of diazepam and valproic acid in the kindling model of epilepsy
J Clin Pharmacol 1981 21: S406 -S412. [Abstract] [PDF]  

DJ Petro and C Ellenberger, Jr

Treatment of human spasticity with delta 9-tetrahydrocannabinol
J Clin Pharmacol 1981 21: S413 -S416. [Abstract] [PDF]  

EA Carlini and JM Cunha

Hypnotic and antiepileptic effects of cannabidiol
J Clin Pharmacol 1981 21: S417 -S427. [Abstract] [PDF]  

P Consroe, A Martin, and V Singh

Antiepileptic potential of cannabidiol analogs
J Clin Pharmacol 1981 21: S428 -S436. [Abstract] [PDF]  

R Karler and SA Turkanis

The cannabinoids as potential antiepileptics
J Clin Pharmacol 1981 21: S437 -S448. [Abstract] [PDF]  

SA Turkanis and R Karler

Electrophysiologic properties of the cannabinoids
J Clin Pharmacol 1981 21: S449 -S463. [Abstract] [PDF]  

JC Merritt, DD Perry, DN Russell, and BF Jones

Topical delta 9-tetrahydrocannabinol and aqueous dynamics in glaucoma
J Clin Pharmacol 1981 21: S467 -S471. [Abstract] [PDF]  

MA Elsohly, E Harland, JC Murphy, P Wirth, and CW Waller

Cannabinoids in glaucoma: a primary screening procedure
J Clin Pharmacol 1981 21: S472 -S478. [Abstract] [PDF]  

HM Deutsch, K Green, and LH Zalkow

Isolation of ocular hypotensive agents from Cannabis sativa
J Clin Pharmacol 1981 21: S479 -S485. [Abstract] [PDF]  

Appendix:

W. Wayne Wiebel

Appendix Guidelines for States Initiating Research on Therapeutic Uses of Marihuana
J Clin Pharmacol 1981 21: 119S -121S. [PDF]  

VIII: OCULAR EFFECTS OF THE CANNABINOIDS:

Sidney Cohen

An Overview of the Symposium
J Clin Pharmacol 1981 21: 486S -487S. [PDF]  

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