J Clin Pharmacol
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First published on July 26, 2007, doi:10.1177/0091270007304105

The Journal of Clinical Pharmacology 2007;47:1172.

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©© 2007 American College of Clinical Pharmacology, Inc.
The Journal of Clinical Pharmacology , 10.1177/0091270007304105

Article

An Informatics Approach to Assess Pediatric Pharmacotherapy: Design and Implementation of a Hospital Drug Utilization System

Athena Zuppa 1*, Sundararajan Vijayakumar 2, Bhuvana Jayaraman 1, Dimple Patel 1, Mahesh Narayan 1, Kalpana Vijayakumar 2, John T. Mondick 1, and Jeffrey S. Barrett 1

1 The Children's Hospital of Philadelphia
2 INTEK Partners Inc

* To whom correspondence should be addressed. E-mail: zuppa{at}email.chop.edu.


  Abstract
Drug utilization in the inpatient setting can provide a mechanism to assess drug prescribing trends, efficiency, and cost-effectiveness of hospital formularies and examine subpopulations for which prescribing habits may be different. Such data can be used to correlate trends with time-dependent or seasonal changes in clinical event rates or the introduction of new pharmaceuticals. It is now possible to provide a robust, dynamic analysis of drug utilization in a large pediatric inpatient setting through the creation of a Web-based hospital drug utilization system that retrieves source data from our accounting database. The production implementation provides a dynamic and historical account of drug utilization at the authors’ institution. The existing application can easily be extended to accommodate a multi-institution environment. The creation of a national or even global drug utilization network would facilitate the examination of geographical and/or socioeconomic influences in drug utilization and prescribing practices in general.
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Copyright © 2007 by the American College of Clinical Pharmacology