J Clin Pharmacol
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The Journal of Clinical Pharmacology and the Journal of New Drugs, 1969; 9:91-98
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Placebo Response in the Evaluation of Hypnotic Drugs

John F. Zaroslinski III. Ph.D.1, Ronald K. Browne III. B.S.2, and Arpad Almassy III. M.D.3

1 Research and Development, Arnar-Stone Laboratories, Inc.; Loyola University School of Medicine, Hines, Illinois.
2 MR. BROWNE is a Senior Pharmacologist, Arnar-Stone Laboratories, Inc., Mount Prospect, Illinois.
3 Chicago State Tuberculosis Sanitarium, Chicago, Illinois.

The results obtained in this investigation with hypnotic drugs indicate that a prescreening of patients on a single-blind basis may be of value in the elimination of patients suffering from mild insomnia or otherwise consistently responsive to placebo. The data further suggest that a three-day period may be optimal for such prescreening.


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Copyright © 1969 by the American College of Clinical Pharmacology