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ANNUAL MEETINGS AND SYMPOSIA

Globalization of Quantitative Pharmacology: First International Symposium of Quantitative Pharmacology in Drug Development and Regulation

Jeffrey S. Barrett, PhD, FCP, Jun Shi, MD, FCP, Hai-tang Xie, PhD, Xiao-hui Huang, PhD, Michael J. Fossler, PharmD, PhD, FCP and Rui-yuan Sun, PhD

From the Laboratory for Applied PK/PD, Clinical Pharmacology & Therapeutics Division, The Children's Hospital of Philadelphia, Pediatrics Department, School of Medicine, University of Pennsylvania (Dr Barrett); Forest Laboratories, Jersey City, New Jersey (Dr Shi); Anhui Provincial Center for Drug Clinical Evaluation, Anhui Province, P.R. China (Dr Xie, Dr Sun); College of Pharmacy, Anhui Medical University, Anhui Province, P.R. China (Dr Huang); and Clinical Pharmacokinetics, Modeling and Simulation, GlaxoSmithKline, King of Prussia, Pennsylvania (Dr Fossler).

The First International Symposium on Quantitative Pharmacology in Drug Development and Regulatory Sciences was held this past October in Nanjing, China, marking the first time scientists from around the globe gathered to discuss topics related to quantitative pharmacology in the Far East. With the recent trend toward global drug development and clinical trials in nontraditional countries, China has been regarded by many as the next frontier for the pharmaceutical industry. Quantitative pharmacology embraces all phases of pharmaceutical research and development, providing a mechanism to bridge decision making from one phase of development to the next, and it facilitates multidisciplinary partnerships through the assembly of both data and models that describe complex biological, biopharmaceutic, and clinical settings. Efforts in China are at an early stage, but it is clear that Chinese scientists embrace the discipline and are keen to promote this methodology in the registration of new drugs in China. While challenges exist, they represent an exciting area of future collaboration.

Key Words: Quantitative pharmacology • globalization • Traditional Chinese Medicine (TCM) • pharmacometrics

Address for reprints: Jeffrey S. Barrett, PhD, FCP, Laboratory for Applied PK/PD, Clinical Pharmacology & Therapeutics Division, The Children's Hospital of Philadelphia, The University of Pennsylvania Medical School, Pediatrics Department, Abramson Research Center, Rm 916H, 3615 Civic Center Blvd, Philadelphia, PA 19104.


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