J Clin Pharmacol
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The effect of pirenzepine on gallbladder emptying in humans

A Keshavarzian, ML Fitzpatrick, A Anagnostides, and VS Chadwick

The effect of the selective antimuscarinic agent, pirenzepine, on gallbladder function was studied in six healthy volunteers, using 99mTc HIDA (N-[2,6-diethylthenyl] carbamoylmethyl iminodiacetic acid) hepatobiliary scanning. Pirenzepine, in doses that inhibit gastric acid secretion, did not alter gallbladder emptying responses to sham feeding stimulation or to a test meal.
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