Pharmaceutical Specialties in the U.S.— A Note About the PDR 1972

¹ Departamento de Ciencias Fisiológicas, Universidad Autónoma de Barcelona, Barcelona, Spain.

This survey was done in order to exploit the possibilities of a widely used compendium, the Physicians" Desk Reference, as a source of information concerning prevalence of fixed-ratio drug combinations (FRC) among prescription drugs in the U.S. Less than half of the products presented in the PDR 1972 were found to be single drug compounds while, at the other end of the spectrum, more than 7 per cent contained more than eight active ingredients. Drug companies showed quite different patterns with regards to marketing of FRC. Fixed-ratio drug combinations accounted for less than 10 per cent of the products offered by 26 companies, while 69 drug firms included between 90 and 100 per cent of FRC in their products listed in the PDR.

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