J Clin Pharmacol
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The Journal of Clinical Pharmacology, 1974; 14:192-201
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The Effect of Lorazepam on Anxious Insomniacs' Sleep as Recorded in the Home Environment

G. Globus M.D.1, E. Phoebus M.A.1, J. Humphries A.B.1, R. Boyd A.B.1, D. Gaffney A.B.1, and S. Gaffney A.B.1

1 Department of Psychiatry and Human Behavior, California College of Medicine, University of California, Irvine, California.

The effect of the benzodiazepine lorazepam on sleep variables in a population of anxious insomniacs and control spouses was studied. Electrophysiological recordings were obtained in the home environment over a five-week period. A tendency towards normalization of the sleep pattern of the insomniacs without suppression of REM sleep is reported. Home recordings proved feasible, and would seem preferable for certain research problems.


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 Arch Gen PsychiatryHome page
B. L. Frankel, R. D. Coursey, R. Buchbinder, and F. Snyder
Recorded and Reported Sleep in Chronic Primary Insomnia
Arch Gen Psychiatry, May 1, 1976; 33(5): 615 - 623.
[Abstract] [PDF]


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Copyright © 1974 by the American College of Clinical Pharmacology