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The Journal of Clinical Pharmacology and New Drugs, 1970; 10:387-389
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Side Effects and Teratogenicity of Lithium Carbonate Treatment

L. Vacaflor M.D.1, H. E. Lehmann M.D.1, and T. A. Ban M.D.1

1 Douglas Hospital, 6875 LaSalle Blvd., Verdun, Quebec, Canada.

In the course of a clinical trial with lithium carbonate in patients suffering from periodic affective disorders, numerous side effects occurred. Among these, tremor and diarrhea were most frequent. Generalized maculopapular rash and alopecia were seen in one patient each, and a toxic confusional state, in four. One patient delivered a malformed baby while on lithium carbonate and chlorpromazine treatment. In the same patient, restriction of salt intake, administration of a diuretic, and suspected unauthorized overdosage of lithium intake induced a severe but reversible comatose state with generalized and focal convulsions.


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This article has been cited by other articles:


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M. Simard, B. Gumbiner, A. Lee, H. Lewis, and D. Norman
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 Arch NeurolHome page
I. MacG. Donaldson and J. Cuningham
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Arch Neurol, November 1, 1983; 40(12): 747 - 751.
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 Arch Gen PsychiatryHome page
B. Reisberg and S. Gershon
Side Effects Associated With Lithium Therapy
Arch Gen Psychiatry, July 1, 1979; 36(8): 879 - 887.
[Abstract] [PDF]


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