J Clin Pharmacol
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First published on September 29, 2009
The Journal of Clinical Pharmacology 2009, doi:10.1177/0091270009348975
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©© 2009 American College of Clinical Pharmacology, Inc.
The Journal of Clinical Pharmacology, 10.1177/0091270009348975

Article

Clopidogrel Before Elective Percutaneous Coronary Intervention

Zuzana Motovska 1* and Petr Widimsky 1

1 Third Medical Faculty of Charles University

* To whom correspondence should be addressed. E-mail: zuzana.motovska{at}iex.cz.


  Abstract
The introduction of percutaneous coronary intervention (PCI) substantially changed the treatment of patients with coronary artery disease. Stent thrombosis is the most worrisome early complication in patients undergoing PCI. Therefore, antiplatelet therapy forms an integral component of treatment with intracoronary stent implantation. A multitude of randomized and observational studies have helped identify and define the role of clopidogrel in today’s PCI patient. Although much is known about its use, a number of questions still remain.
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Copyright © 2009 by the American College of Clinical Pharmacology